人群碘营养状况的监测指标—新生儿TSH水平的应用研究  

STUDY ON USAGE OF NEONATES' TSH LEVEL AS AN INDEX FOR NUTRITIONAL STATE OF IODINE

作　　者：王刚 钱俊楠 宋继成 夏兴焕 赵文彬 

机构地区：[1]连云港市妇幼保健医院检验科,连云港222006

出　　处：《现代预防医学》2008年第7期1241-1243,共3页Modern Preventive Medicine

摘　　要：[目的]探讨新生儿足跟血TSH水平作为人群碘营养状况监测指标应用的可行性。[方法]采用时间分辨荧光免疫法(TRFIA)筛查新生儿足跟全血(72h后)TSH值。[结果]在人群,环境碘营养状况基本符合碘缺乏病消除标准,新生儿筛查率达94.99%(2006),新生儿TSH﹥5μlu/ml为2.47%(3833/155315);各年度确诊CH病儿比率差异无统计学意义(P﹥0.05)。[结论]在碘缺乏病基本消除地区采用TRFIA法筛查CH,其新生儿TSH水平可作为人群的碘营养状况的监测指标之一。[Objective] To explore the possibility on usage of the level of neonates＇ Thyroid Stimulating Hormone （TSH） in heel blood as an index nutritional state of iodine. [Methods] Used time-resolved fluorescent inmmnoassay （TRFIA） to analyze TSH in heel blood after 72 hours. [Results] In population, the environmental nutrition state of iodine basically accorded with the standard of removing IDD. Screening rate of neonates was 94.99% （2006）. The percentage of using TRFIA to test the level of TSH in neonates＇ blood over 5μlu/ml was 2.47% （3 833/155 315）. [ConclusiOn] It is a good way to screen CH by using TRFIA in the region where the iodine deficiency disease is basically removed, the neonates＇ TSH level could be as one of monitoring indexes on nutritional state of iodine.

关 键 词：新生儿 促甲状腺激素 碘 营养状况 时间分辨荧光免疫法 

分 类 号：R339.31[医药卫生—人体生理学]