^(18)F-FDG PET/CT显像对不明原因腹水的诊断价值  

Value of ^(18)F-FDG PET/CT in diagnosing the unknown cause of ascites

作　　者：谭海波[1] 闫瑾[1] 赵军[1] 管一晖[1] 华逢春[1] 左传涛[1] 张政伟[1] 王红兵[1] 林祥通[1] 

机构地区：[1]复旦大学附属华山医院核医学科PET中心,上海200235

出　　处：《中国临床医学影像杂志》2008年第3期178-180,共3页Journal of China Clinic Medical Imaging

摘　　要：目的:评价18F-FDG PET/CT对不明原因腹水的诊断价值。方法:对经B超、胃肠内窥镜和(或)消化道造影、CT和(或)MRI、各种生化和腹水细胞学检查无法确定病因的22例腹水患者进行18F-FDG PET/CT全身显像。受试者做完PET/CT检查后,由两位有经验的医师独立阅片。结果判断应用目测法和半定量分析方法(标准摄取值,SUV)。结果:22例腹水原因待查的患者行PET/CT检查后,经病理及随访证实其中恶性腹水14例,其它原因所致腹水4例,不明原因者4例。14例恶性腹水患者中,7例PET/CT可检出原发灶(50%),7例假阴性。4例其它原因所致腹水中,3例经PET/CT检查后明确了病因,另1例为结核性腹膜炎,PET/CT误诊为恶性病变。总的诊断符合率为45.5%(10/22)。结论:在腹水病因探查中,18F-FDG PET/CT显像与其它传统影像学检查相比是一种更为有效、灵敏的手段。Objective： To evaluate the diagnostic value of ^18F-FDG PET/CT for the patients with ascites of unknown causes. Methods： Twenty-two patients with ascites of unknown cause refered to our department for whole-body ^18F-FDG PET/ CT. The causes of their ascites could not be confirmed by ultrasound, endoscope and/or radiographic imaging, CT and/or MRI, and diagnostic paracentesis for biochemical content and cytology. The images were interpreted by visual inspection and semi- quantitative analysis（standardized uptake value, SUV）. Results： According to the results of follow-up and pathology, 14 patients were confirmed as malignant ascites, 4 ascitic patients were caused by other reasons, the causes of ascites were still unknown in 4 patients. In the 14 patients of malignant ascites, in 7 patients primary focus were found by ISF-FDG PET/CT and 7 patients were false negative. 10/22 cases （45.5%） were correctly diagnosed. Conclusions： ^18F-FDG PET/CT was a more sensitive and effective method in finding the causes of ascites compared with traditional imaging methods.

关 键 词：腹水 放射性核素显像 

分 类 号：R442.5[医药卫生—诊断学] R817.4[医药卫生—临床医学]