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作 者:蒋宝琦[1] 王伟民[1] 于江宏 陈步星[1] 吴淳[1] 刘喜荣
出 处:《北京医科大学学报》1997年第5期456-458,共3页Journal of Peking University(Health Sciences)
摘 要:目的:了解经皮腔内冠状动脉成形术(PTCA)中人类心脏能否被预适应。方法:分析冠心病患者行PTCA术治疗25例临床资料,并比较第1、2两次球囊充盈扩张时体表心电图ST段变化。结果:尽管第2次球囊扩张时限比第1次长10,4S(P<0.05),但球囊第2次充盈时心电图ST段变化比第1次的小2mm(P<0.05)。结论:PTCA术中球囊充盈扩张所致短暂缺血可能使心脏对缺血的耐受性增强。Objective: To observe whether there were ischemic preconditioning during percutaneous translurninal coronary angioplasty procedures in human hearts. Methods: To analyse clinical data of 25 patients with coronary artery disease during PTCA procedures for comparing ST segment changes on body surface ECG between the first and second bal1oon inflations. Results: ST segment changes on ECG during the second balloon inflation was fewer than those during the first one by 2 mm (P < 0. 05 ), even though the balloon inflation time during the second one was longer than that during the first one by 10. 4 s (P < 0. 05 ).Conclusion:Transient myocardial ischemia during the balloon inflation on PTCA procedures made the heart enhance its ability to tolerate myocardial ischemia.
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