低剂量多巴酚丁胺超声心动图预测经皮腔内冠脉成形术后冬眠心肌功能改善的价值  

Low-Dose Dobutamine Echocardiography Predicts Improvement of Hibernating Myocardium after Percutaneous Transluminal Coronary Angioplasty

作　　者：宾建平[1] 刘伊丽[1] 李崇信[1] 秦建新[1] 王国英[1] 彭健[1] 侯玉清[1] 

机构地区：[1]广州第一军医大学南方医院心内科,510515

出　　处：《中国超声医学杂志》1997年第10期48-50,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：对经皮腔内冠脉成形术（PTCA）成功的24例慢性冠心病患者术前低剂量多巴酚丁胺超声（DE）和术后平静超声（38．3天）进行分析。结果：术前基础状态室壁运动异常154节段；DE心肌收缩力储备阳性84节段（54．5％），PTCA术后功能改善91节段（59．1％），P＞0．05。以DE心肌收缩力储备阳性预测PTCA术后节段室壁运动改善，敏感性84．6％、特异性88．9％、阳性预测值91．7％、阴性预测值80％。结果表明：DE可识别冬眠心肌和准确地预测PTCA术后局部左室功能的改善。Twenty-four patients with chronic coronary artery disease underwent echocardiography at rest and lowdose dobutamine echocardiography (DE) before successful percutaneous transluminal coronary angioplasty (PTCA), and postoperative echocardiography at 38. 3±6. 8 days after PTCA.All echocardiograms were analyzed in blinded fashion. The results: 154 segments had abnormal wall motion at rest. 84 (54.5%) of those segments had response to dobutamine, and 91(58.4%) of those segments improved function after PTCA (P>0.05). A positive response to dobutamine predicted improvement of segmental left ventricular dysfunction after PTCA, sensitivity and specificity were 84.6% and 88.9%, respectively,whereas positive and negative predictive accuracy were 91.7% and 80%. respectively. Conclusions: DE is an useful technique for accurately identifying hibernating myocardium and highly predicting the improvement of segmental left ventricular dysfunction after PTCA.

关 键 词：超声心动图 多巴酚丁胺 冬眠心肌 冠脉成形术 

分 类 号：R654.2[医药卫生—外科学] R541.405[医药卫生—临床医学]