超声造影时间强度曲线分析在乳腺肿瘤诊断中的应用  

Application of time-intensity curve of contrast-enhanced ultrasonography in the diagnosis of breast masses

作　　者：张渊[1] 江泉[1] 陈剑[1] 顾晓鸣[2] 

机构地区：[1]浦东新区人民医院超声科,201200 [2]浦东新区人民医院统计室,201200

出　　处：《上海医学影像》2008年第1期15-17,共3页Shanghai Medical Imaging

基　　金：上海市浦东新区社会发展局卫生科技资助项目(编号:PWZXK2007-02)

摘　　要：目的探讨超声造影时间强度曲线分析对乳腺肿瘤的诊断价值。方法49例乳腺肿块患者(22例良性,27例恶性),选用声诺维(SonoVue)作为超声造影剂,观察造影后血流增强程度并用软件进行时间强度曲线分析。结果超声造影后恶性组血流信号高增强例数明显高于良性组,差异有显著性意义(P<0.05)。乳腺良恶性肿块时间强度曲线形态及参数存在差异。恶性组到达时间、达峰时间均短于良性组(P<0.05),恶性组的上升支斜率、峰值强度均大于良性组(P<0.05)。结论超声造影时间强度曲线分析有助于鉴别乳腺良恶性肿瘤。Objective To discuss the diagnostic value of time-intensity curve analysis of contrast-enhanced uhrasonography（CEUS） in the diagnosis of breast masses. Methods Totally, 49 patients with breast masses （22 benign, 27 malignant） were examined with CEUS . SonoVue was used as a contrast media. The dynamic CEUS images were analyzed with the time-intensity curve software. Results After contrast agent injection, high enhancement cases in malignant group were more than those in benign group. The correlation between benign and malignant lesions was stastically significant（P〈0.05）. There was statistical difference between breast benign and malignant tumors in configuration and parameters on time-intensity curve. The arrival time and the time to peak enhancement were shorter in malignant group than those in benign group（P〈0.05）. The slope of the rising part and peak intensity was greater in malignant group than that in benign group（P〈0.05）. Coulusion Time-intensity curve analysis of contrast-enhanced ultrasonography is helpful in differentiating diagnosis of breast masses.

关 键 词：超声检查 造影剂 乳腺肿瘤 

分 类 号：R981[医药卫生—药品] R764.21[医药卫生—药学]