老年人高血压左心室肥厚与血压变异性及Q-T间期离散度的关系  

Relations between left ventricular hypertrophy,blood pressure variability and Q-T dispersion in elderly patients with essential hypertension

作　　者：汤凤英[1] 桑更生[1] 王顺[2] 

机构地区：[1]安徽省蚌埠市第三人民医院心血管内科,安徽蚌埠233000 [2]安徽省蚌埠市第三人民医院彩超室,安徽蚌埠233000

出　　处：《蚌埠医学院学报》2008年第2期169-170,173,共3页Journal of Bengbu Medical College

摘　　要：目的：探讨老年人高血压左心室肥厚（LVH）与血压变异性（BPV）及Q-T间期离散度（QTcd）之间的关系。方法：选择69例门诊及住院的老年高血压患者（≥60岁）,进行超声心动图检查、24h动态血压监测、静息同步12导联心电图检查,测左室重量指数、QTcd及BPV等相关参数。结果：LVH组平均左室重量指数为（158.68±23.57）g/m^2,明显高于左心室正常组（P〈0.001）;LVH组24h收缩压变异系数、白天、夜间收缩压变异系数、校正QTcd均明显高于LVH组（P〈0.01-P〈0.001）。结论：老年患者高血压LVH与BPV有关,LVH是心律失常、猝死的独立危险因素,BPV可作为降压治疗的新目标。Objective：To explore the relations between left ventricular hypertrophy （LVH） , blood pressure variability（BPV） and QTcd in elderly patients with essential hypertension （ EH ）. Methods ： Sixty-nine elderly patients with EH essential hypertension were performed echocardiography, 24 h ambulatory blood pressure monitoring and 12-lead synchronous resting electrocardigram. The left ventricular mas indexes（ LVMI）, QTcd and the BPV were measured with echocardiography. Results：The average LVMI of myocardium hypertrophy group was （ 158.68 ± 23.57 ） g/m^2 , which was significantly increased compared with that of the control group （ P 〈 0. 001 ）. The 24 h SBPV ,dSBPV,nSBPV and QTcd of the EH patients with LVH were significantly higher than those of EH patients without LVH （P 〈0.01 -P 〈 0. 001 ）. Conclusions： The study suggests that LVH is correlated with BPV. LVH is the risk factor for cardiac dysrhythmia and sudden death. Control of BPV should be considered in treatment of elderly patients with EH.

关 键 词：高血压/并发症 左心室肥厚 血压变异性 Q-T间期离散度 老年病学 

分 类 号：R541.3[医药卫生—心血管疾病]