聚乙二醇预处理脂血标本前后FT_3和FT_4的变化  

Changes of free triiodothyronine and free thyroxin in high lipid serum pretreated by polyethylene glycol

作　　者：叶志恒[1] 储小宏[1] 贾丽[1] 赵广碧[1] 吴帮庆[1] 

机构地区：[1]安徽医科大学第一附属医院内分泌实验室,安徽合肥230022

出　　处：《蚌埠医学院学报》2008年第2期225-226,共2页Journal of Bengbu Medical College

摘　　要：目的:探讨用聚乙二醇(polyethylene glycol,PEG)预处理脂血标本前后游离三碘甲状腺原氨酸(FT3)和游离甲状腺素(FT4)的变化。方法:将28名正常人组和20例脂血组的血清分两份,一份直接测定,另一份用95g/LPEG液处理标本后,再以放射免疫法测定FT3和FT4。结果:正常人组PEG处理前后,FT3和FT4检测结果差异均无统计学意义(P>0.05);而脂血标本组用PEG处理前FT3和FT4检测结果显著高于PEG处理后(P<0.001)。结论:正常情况下,PEG处理标本不影响FT3和FT4检测。标本经PEG处理后,去除脂质、甲状腺激素自身抗体的干扰,提高结果的准确性。Objective：To investigate the changes of free triiodothyronine （FT3 ） and free thyroxin （FT4 ） in high lipid serum pretreated by polyethylene glycol （PEG）. Methods：The specimen were divided into two groups：one was directly tested,the other was pretreated by PEG. FT3 and FT4 of the normal and high lipid serum were measured by radio immunoassay. Results：Compared with that directly tested in the normal group, the level of FT3 and FT4 had no statistic difference compared to the pretreated by PEG （ P 〉 0.05 ）. The results of high lipid serum pretreated by PEG were markedly decreased compared to the directly tested （ P 〈 0.001 ）. Conclusions ： As the high lipid and thyroid hormone auto antibody is eliminated by PEG, the accuracy is improved.

关 键 词：放射免疫测定 聚乙二醇 三碘甲状腺原氨酸 甲状腺素 血脂过多 

分 类 号：R446.62[医药卫生—诊断学] R979.9[医药卫生—临床医学]