桥脑内侧网状结构,值得重视的麻醉靶位  

Medial pontine reticular formation: a potential anesthetic target

作　　者：王嘉锋[1] 李文献[2] 王雪琦[1] 

机构地区：[1]第二军医大学基础部神经生物学教研室,上海200433 [2]第二军医大学长海医院麻醉科,上海200433

出　　处：《第二军医大学学报》2008年第3期334-336,共3页Academic Journal of Second Military Medical University

摘　　要：桥脑内侧网状结构是脑干网状结构的重要组成部分之一,近年来受到麻醉医师的广泛关注,因为该部位不仅与意识状态密切相关,与镇痛、肌松及自主神经反射抑制也有一定关联,而这些正是麻醉医师所关注的麻醉效应。有关桥脑内侧网状结构的深入研究,可能对全身麻醉作用机制的探索提供有力依据,同时可能使其成为有效的麻醉靶位,从而在提供充分的麻醉效应的同时减少麻醉并发症的发生。Medial pontine reticular formation （mPRF） ,an important part of brainstem reticular formation,has drawn great attention from anesthesiologists due to its close relation with not only consciousness, but also analgesia, muscle relaxation and autonomic reflex. Progress in related research may provide evidence for understanding the mechanism of general anesthesia; meanwhile,it may serve as an effective anesthesia target site,which may contribute to improvement in anesthetic effect and re- duction of complications.

关 键 词：桥脑内侧网状结构 胆碱能神经元 全身麻醉 

分 类 号：R614.2[医药卫生—麻醉学]