四种左室心肌组织多普勒成像技术定量测量冠状动脉狭窄的比较  

Comparative study on four techniques of tissue Doppler imaging in measuring left ventricular myocardial movement in coronary artery stenosis

作　　者：张生光[1] 俞静[1] 汪荣金[1] 陈爱[1] 骆合德[1] 

机构地区：[1]解放军第98医院超声科,浙江湖州313000

出　　处：《心脏杂志》2008年第2期169-172,共4页Chinese Heart Journal

摘　　要：目的应用组织多普勒成像4种技术研究左室局部心肌速度、形变、位移及同步性变化与冠状动脉狭窄程度之间的定量关系。方法应用定量组织速度成像(QTVI)、应变及应变率成像(SI和SRI)、组织追踪(TT)和组织同步化成像(TSI)定量分析23例冠心患者和31例正常人左室局部心肌收缩期(Vs)、舒张早期(Ve)和舒张晚期峰值速度(Va);收缩末期(εsys)、峰值(εp)和收缩后应变(εps)及R波到峰值应变的时间(T-εp);收缩期(SRs)、等容舒张期(SRir)、舒张早期(SRe)及舒张晚期峰值应变率(SRa);收缩期峰值位移(Ds)、R波至收缩期位移峰值的时间(T-ds)及收缩速度达峰时间(Ts)等指标。结果在中重度狭窄组中εsys、εp、SRs、SRir、SRe及Vs、Ve、Ds降低,εps、T-ds、T-εp和Ts则明显增加,与正常组相比具有显著意义或非常显著意义(P<0.05或P<0.01)。结论QT-VI、SRI、TT和TSI均能较准确地检出中重度冠状动脉狭窄患者静息状态下的异常心肌节段。AIM To compare the diagnostic value of quantitative tissue velocity imaging （QTVI）, strain and strain rate imaging （SI and SRI）, tissue tracking （TY） and tissue synchronization imaging （TSI） in observing the changes of left ventricular myocardial movement in patients with coronary heart disease. METHODS Thirty-one normal subjects （control group） and 23 cases （stenosis group） with coronary artery stenosis verified by coronary arteriography were enrolled in this study. In each case, 12 left ventricular segments were analyzed and 14 indexes were obtained and compared between the two groups. The 14 were velocity during systole （Vs）, early diastole （Ve）, artrial contraction （Va）, peak strain （εp）, end-systolic strain （εsys）, postsystolic strain （εps）, time from R wave to peak strain （T-εp）, the peak strain rate at systole （SRs）, isovolumic relaxation （SRir）, early diastole （SRe）, atrial contraction （SRa）, displacement at systole （Ds）, time from R wave to peak displacement （T-ds） and systolic velocity time to peak （Ts）. RESULTS Compared with those in control group, εsys, εp, SRs, SRir, SRe, Vs, Ve and Ds decreased and εps, T-ds, T-εp and Ts significantly increased in the moderate and severe-stenosis groups （P 〈 0.05 and P 〈 0.01, respectively）. CONCLUTION QTVI, SRI, TY and TSI can fairly accurately detect the abnormal segments in patients with moderate or severe coronary artery stenosis at rest.

关 键 词：定量组织速度成像 应变率成像 组织追踪 组织同步化成像 冠状动脉狭窄 冠状动脉造影 

分 类 号：R543.3[医药卫生—心血管疾病]