G9型人A组轮状病毒LL52696与LL52727株的主要基因及其编码蛋白特征的分析  

Characteristics Analysis on Major Genes and the Encoded Proteins of Human G9P[8] Rotaviruses LL52696 and LL52727

作　　者：李丹地[1] 崔淑娴[2] 章青[2] 靳淼[2] 虞结梅[2] 张栋梁[2] 徐子乾[2] 唐景裕 王忠山[1] 方肇寅[2] 段招军[2] 

机构地区：[1]吉林大学白求恩医学院,吉林长春130021 [2]中国疾病预防控制中心病毒病预防控制所,北京100052 [3]河北省卢龙县疾病预防控制中心,石家庄050000

出　　处：《病毒学报》2008年第2期144-147,共4页Chinese Journal of Virology

摘　　要：Two Rotavirus G9P[8] strains (LL52696 and LL52727) were recognized during a sentinel-based survey in Lulong, China. Phylogenetic analysis of the VP7 gene showed that both strains isolated constituted a divergent genetic cluster distinct from the other G9 strains isolated in China. Analysis of VP4, VP6, and NSP4 genes revealed that these strains were closely related to Lulong strains. We hold that two strains were reassortant between G9 and Lulong predominant strains.Two Rotavirus G9P[8] strains （LL52696 and LL52727） were recognized during a sentinel-based survey in Lulong, China. Phylogenetic analysis of the VP7 gene showed that both strains isolated constituted a divergent genetic cluster distinct from the other G9 strains isolated in China. Analysis of VP4, VP6, and NSP4 genes revealed that these strains were closely related to Lulong strains. We hold that two strains were reassortant between G9 and Lulong predominant strains.

关 键 词：人A组轮状病毒 G9P[8] VP7 VP4 VP6 NSP4 

分 类 号：R372.2[医药卫生—病原生物学]