着丝粒结构与功能研究的新进展  

Research Progress on the Structure and Function of Centromeres

作　　者：丁戈[1] 姚南[2] 吴琼[1] 刘恒[1] 郑国锠[1] 

机构地区：[1]兰州大学生命科学学院细胞生物学研究所,兰州730000 [2]兰州大学第一医院,兰州730000

出　　处：《植物学通报》2008年第2期149-160,共12页Chinese Bulletin of Botany

摘　　要：着丝粒是真核生物染色体的显著特征。在细胞有丝分裂和减数分裂中,着丝粒作为保证染色体正常分裂并分离到子细胞的结构和功能元件,参与了同源染色体配对、姐妹染色单体黏合、分离及分裂后期启动的调控等。本文对近年来着丝粒结构和功能研究的新进展进行了概述。As the remarkable characteristic of every eukaryotic chromosome, the centromere is the structural and functional element that ensures the normal split and separation of chromosomes during mitosis and meiosis. It is involved in processes such as homologous chromosome pairing, sister chromatid adhesion and separation, and some of the regulation initiated during anaphase. Here we review some of recent progress in research into the structure and function of centromeres.

关 键 词：着丝粒 表观遗传学 RNA干扰 

分 类 号：Q343[生物学—遗传学]