出血分级在特发性血小板减少性紫癜患者中的临床意义  

Clinical significance of bleeding grading in patients with idiopathic thrombocytopenic purpura

作　　者：王晓燕[1] 李晶晶[2] 陈振萍[1] 葛菁 季林祥[1] 杨仁池[1] 

机构地区：[1]中国医学科学院中国协和医科大学血液学研究所血液病医院,天津300020 [2]南开大学医学院

出　　处：《山东医药》2008年第10期11-13,共3页Shandong Medical Journal

基　　金：国家自然科学基金资助项目(30670900);公益性卫生行业科研专项基金项目(200802031)

摘　　要：目的探讨出血分级在特发性血小板减少性紫癜(ITP)中的临床意义。方法采用自拟ITP出血分级标准对225例ITP患者进行出血分级,采用双变量分析出血分级与PLT计数及疗效的关系。结果ITP最常见的出血部位为皮肤,致命性内出血少见。出血分级与PLT计数呈负相关,与疗效呈正相关,但相关关系不密切。结论ITP患者的出血危险与PLT计数不呈绝对反比,临床出血程度较PLT计数更重要;对ITP患者进行出血分级有助于监测出血,选择治疗策略,预测疗效。Objective To explore the clinical significance of bleeding grading in patients with idiopathic thrombocytopenic purpura（ITP）. Methods Bleeding grading was developed for 225 patients with ITP by means of ITP bleeding grading standard, the relationships of bleeding grading platelet count and curative effect were analyzed by means of couple analysis of variance. Results The most frequent bleeding site was skin and the occurrence of llfe-threatening hemorrhage was a rare event in ITP. Bleeding grading was negatively correlated to the platelet count and positively correlated to the curative effect（ but there were no close correlativities） Conclusions Bleeding severity in ITP is negatively correlated to the platelet count. Bleeding severity is more important than platelet count. Bleeding grading helps to monitor hemorrhage, make management decisions and predict curative effect.

关 键 词：紫癜 血小板减少性 特发性 出血分级 血小板计数 

分 类 号：R554.6[医药卫生—血液循环系统疾病]