1,5-脱水山梨醇对糖尿病早期诊断的意义  

Significance of 1,5-anhydro-D-g1ucito1 in the Early Diagnosis of Diabetes

作　　者：张颖[1] 朱铁虹[2] 

机构地区：[1]天津医科大学,天津300070 [2]天津医科大学总医院内分泌科,天津300052

出　　处：《医学综述》2008年第7期1077-1079,共3页Medical Recapitulate

摘　　要：血清1,5-脱水山梨醇(1,5-AG),又称1,5-脱水葡糖醇,是一种较新的糖尿病诊断和治疗监测指标,它是在人的脑脊液中首先被发现的。1,5-AG是一种存在于人类血液中的正常化合物,由于其代谢稳定,在血液中波动范围小,可反映血糖短期的变化,糖尿病患者血糖升高时,1,5-AG浓度明显降低,血糖下降后1,5-AG回升,具有空腹血糖、果糖胺和糖化血红蛋白所不具有的优点,在糖尿病早期诊断与治疗中具有很高的价值和意义。Serum 1,5-anhydro-D-ghlcitol （ 1,5-AG）, also known as 1,5 anhydro - sorbitol, ,is a relatively new indicator in its diagnosis and therapeutic monitoring.. It is first found in the human ncurolymph. This substance is a normal compound existed in human blood, which can reflect the changes of blood sugar in short term because its stable metabolism and little fluctuation in blood. When the blood sugar of patients with diabetes is increased, the level of this substance will be decreased obviously, Once the blood sugar is lowered again, the level of this substance will be increased again. It has some advantages that any other indexes have not, including fasting blood glucose, fmctosamine and glycosylated hemoglobin, The detection of 1,5 anhydro - sorbitol has high value and significance in the early diagnosis and therapy of diabetes.

关 键 词：1 5-脱水山梨醇 糖尿病 早期诊断 葡萄糖 果糖胺 糖化血红蛋白 

分 类 号：R587.1[医药卫生—内分泌]