肝脏良恶性病变的多层螺旋CT动态灌注成像评估  

Perfusion Imaging of Benign and Malignant Lesions in the liver with Multi-slice Spiral CT

作　　者：邵康为[1] 杨军[1] 刘伟[1] 朱才松[1] 袁立新[1] 诸瑛[1] 李崧[1] 

机构地区：[1]上海市长宁区中心医院影像科,200336

出　　处：《临床放射学杂志》2008年第3期339-342,共4页Journal of Clinical Radiology

基　　金：上海市医学重点专科建设及科研基金资助(编号:05II025)

摘　　要：目的探讨肝脏良恶性病变的CT动态扫描及灌注成像特点。资料与方法比较分析33例肝脏良恶性病变的CT动态增强扫描的时间-密度曲线的类型。结果恶性肿瘤(n=25)与良性病变(n=8)表现为不同类型的时间-密度曲线。良恶性病变的平均血流量(BF)分别为(408.8794±84.42)ml·min-1·ml-1和(766.621±55.304)ml·min-1·ml-1,恶性病变的血流量明显增高(P=0.0375)。良恶性病变的平均血容量(BV)分别为(23.4658±3.989)ml·min-1·ml-1和(56.7256±7.16)ml·min-1·ml-1,恶性病变的血容量明显增高(P=0.0029)。结论肝脏良恶性病变表现为不同类型的时间-密度曲线,根据时间-密度曲线的类型可帮助鉴别肝脏良恶性病变。Objective To investigate perfusion imaging features of benign and malignant lesions in the liver with dynamic enhancement CT. Methods The type of the time-density curve obtained by dynamic enhancement CT in 33 cases with benign and malignant lesions in the liver was analyzed. Results Benign and malignant lesions showed dif- ferent type of time - density curve on dynamic enhancement CT. The average value of blood flow （BF） of benign and malignant lesions was （408. 8794 ± 84.42） ml · min^-1·ml^-1 and （766.621 ± 55. 304 ） ml · min^-1·ml^-1 , respectively with the average value of BF of malignant lesions higher than that of benign lesions （ P = 0. 0375 ）. The average value of blood volume（BV） of benign and malignant lesions was（23. 4658 ± 3. 989） ml · min^-1·ml^-1 （56.7256 ± 7.16） ml · min^-1·ml^-1 , respectively with the average value of BV of malignant lesions higher than that of benign lesions（P = 0. 0029）. Conclusions Benign and malignant lesions in the liver showed different type of time -density curve on dynamic enhancement CT, which could be applicable to differentiate between benign and malignant lesions.

关 键 词：肝脏 肿瘤 体层摄影术 X线计算机 灌注 

分 类 号：R816.5[医药卫生—放射医学]