黄热病疫苗接种的危险因素评估及不良反应的预防  

Evaluation of Risk Factors of Yellow Fever Vaccine and Prevention of Side Reaction

作　　者：朱俊贤[1] 蔡翁义[1] 

机构地区：[1]汕头出入境检验检疫局,汕头515041

出　　处：《旅行医学科学》2008年第1期43-45,共3页

摘　　要：目的探讨黄热病减毒活疫苗接种后可能发生的不良反应及引起不良反应的可能危险性因素,提出预防措施。方法对世界各国在接种黄热病减毒活疫苗后出现不良反应的有关文献资料、以及我国检验检疫部门在开展黄热病疫苗接种工作中的实际情况进行综合分析。结果黄热病减毒活疫苗接种后可能出现包括YEL-AND和YEL-AVD等严重并发症在内的各种不良反应,其发生与疫苗的自身情况及接种对象的体质、健康、生理状况密切相关。结论为防止各种严重不良反应的发生,实施接种人员应根据接种者的机体情况及其在旅行过程暴露于黄热病的危险程度,做出危险性评估,决定其有无接种必要。同时要加强疫苗管理,保证疫苗质量,做好疫苗使用后的监测工作。Objective To Discuss the side reaction and the possible risk factors of side reaction after inoculating Attenuated Yellow Fever Vaccine Live, and put forward preventive measures. Methods To carry on comprehensive analysis of literature and data of general side reaction inoculating Attenuated Yellow Fever Vaccine Live in foreign countries and inspection and quarantine organizations in our country. Results It may cause varied side reaction, including YEL-AND, YEL-AVD etc. severe complication, which are closely related with vaccine status, and constitution, health status and physiological status of acceptors. Conclusion In order to prevent the side reaction, the inoculator should take evaluation of health status of acceptors and analyze the risk of acceptor exposing to Yellow Fever during the travel. Then make sure if it is necessary to carry out inoculate. We also should be strengthen management to the vaccine, guarantee quality of vaccine and do well postvaccinal surveillance.

关 键 词：黄热病疫苗 不良反应 预防 

分 类 号：R186[医药卫生—流行病学]