正交试验法优选补骨脂的盐炙工艺  

Optimal Salt-roast Process of Psoralea corylifolia L.by Orthogonal Design

作　　者：林辉[1] 胡昌江[1] 李兴迎[1] 余凌英[1] 黄勤挽[1] 李兴华[1] 李金连[1] 陈杰[1] 胡昌河 

机构地区：[1]成都中医药大学,四川成都610075 [2]四川省达县中医院,四川达县635000

出　　处：《中国药业》2008年第7期35-36,共2页China Pharmaceuticals

基　　金：国家十一五科技支撑计划项目;项目编号:2006BAI09B06-09

摘　　要：目的研究补骨脂盐炙的最佳工艺条件,探索其共性技术。方法采用正交试验设计法,以补骨脂素为指标筛选最佳工艺。结果补骨脂盐炙最佳工艺为补骨脂药材500g,加食盐水250mL(取10g食盐加水至250mL),室温闷润24h,置150℃锅中,以40次/min的翻炒频率,炒炙10min。结论该工艺稳定可行。Objective To investigate the best process for salt- roast of Psoralea corylifolia L.Methods Several orthogonal designs were adopted for screening. Results The optimal process was to soak Psoralea corylifolia k 500 g with 0.04 g/mL salt solution 250 mL at the ordinary temperature for 24 h, and then roast for 10min at 150℃, overturning 40 times per minute. Conclusion The optimized method is stable and efficient, and it is available for further investigation into Psoralea corylifolia k.

关 键 词：补骨脂 盐炙工艺 正交试验 总香豆素 

分 类 号：R283.3[医药卫生—中药学] R282.71[医药卫生—中医学]