腰穿放液后脑血流变化预测正常压力脑积水分流效果的研究  

Prediction of the Effect of Normal Pressure Hydrocephalus Shunt by the Change of Cerebral Blood Flow after Drainage of Cerebrospinal Fluid with Lumbar Puncture

作　　者：方强[1] 王志强[1] 朱子健[1] 

机构地区：[1]湖南省马王堆医院神经外科,湖南长沙410016

出　　处：《医学临床研究》2008年第3期482-483,共2页Journal of Clinical Research

摘　　要：【目的】通过腰穿放液前后脑血流变化预测正常压力脑积水(NPH)患者行分流手术的效果。【方法】回顾性分析26例NPH患者腰穿放液前后脑血流变化与脑室-腹腔(V-P)分流术后效果的相关性。【结果】分流术后2个月患者症状改善与腰穿放液前后脑血流的变化呈正相关,其中症状改善显效和有效患者腰穿后脑血流速度较前明显增加,而无效患者前后差异无统计学意义。【结论】腰穿放脑脊液前后脑血流的变化可作为预测NPH患者行分流手术疗效的指标。[Objective]To predict the effect of normal pressure hydrocephalus（NPH） shunt through drainage of cerebrospinal fluid with lumbar puncture. [Methods] The correlation between the difference of cerebral blood flow of 26 cases with NPH and the （V-P）shunting was retrospectively analyzed. [Results]The curative effect positively correlated with the difference of cerebral blood flow with pre- and post-drainage of cerebrospnal fluid with lumbar puncture. The brain blood flow of patie, nts whose symptom approved effective had evidently increased after 2 month of shunting, but the difference of brain blood flow of ineffective cases had no statistical significance. [Conclusion]The difference of brain blood flow after drainage of cerebrospinal fluid with lumbar puncture may be a guideline to predict the curative effect of shunting.

关 键 词：脊椎穿刺 脑积水 正常压力/外科学 脑血管循环 预测 预后 

分 类 号：R651.11[医药卫生—外科学]