N-硝基-2,4,6-三硝基苯基脲衍生物的合成及除草活性  

Synthesis of N-Nitro-2,4,6-trinitrophenyl Urea Derivatives and Their Herbicidal Activities

作　　者：江洪[1] 方利[1] 崔燕[1] 

机构地区：[1]华中农业大学化学系,武汉430070

出　　处：《农药》2008年第4期252-254,共3页Agrochemicals

基　　金：国家自然科学基金(No.39770845);华中农业大学博士基金项目(52204-05047)

摘　　要：2,4-二硝基苯胺与乙酰硝酸酯反应生成N-硝基-2,4,6-三硝基苯胺,N-硝基-2,4,6-三硝基苯胺与固体光气在甲苯中反应,生成酰氯中间体,酰氯中间体再与取代苯胺反应得到7种含N-硝基的不对称脲类化合物,产物经IR、1HNMR、质谱、元素分析表征。初步测试结果表明,当质量浓度为500mg/L时,化合物具有良好的抑制苋菜与稗草活性,部分化合物对苋菜的死亡率达到100%。N-Nitro-2,4,6-trinitroaniline was produced by treating 2,4-dinitroaniline with acetyl nitrate. Then it was converted to carbamoyl chloride by treating it with bis（trichloromethyl）carbonate in toluene. Treatment of the acid chloride with substituted anilines gave 7 novel N-nitro-2,4,6-trinitrophenyl urea derivatives. Their structures were confirmed by ^1H NMR, IR, MS and elemental analysis. Preliminary biological test results showed that some of these target compounds had good herbicidal activities against Portulaca olercea and Echinochloa crus-galli, and some compounds cause 100% death to Portulaca olercea at the concentration of 500 mg/L.

关 键 词：N-硝基-2  4  6-三硝基苯胺 固体光气 脲 除草活性 

分 类 号：TQ457.2[化学工程—农药化工]