BiPAP治疗慢性充血性心力衰竭26例患者疗效观察  

Application of noninvasive bi-level positive airway pressure ventilation to patients with severe congestive heart failure

作　　者：鲁四德[1] 阮鹏[1] 杨皓[1] 王波[1] 田磊[1] 韩坷[1] 

机构地区：[1]湖北省十堰市郧阳医学院附属人民医院ICU,湖北十堰442000

出　　处：《中国现代医学杂志》2008年第5期613-615,共3页China Journal of Modern Medicine

摘　　要：目的探讨无创双水平气道正压通气(BiPAP)对重度充血性心力衰竭的作用。方法选择26例次经常规方法治疗无效的重度充血性心力衰竭患者进行BiPAP,记录临床症状体征、Boston心衰积分、彩色多普勒二维超声心动图、血气分析及运动耐力等指标监测。结果26例重度充血性心力衰竭患者抢救成功21例次,抢救成功率80.8%。治疗后生命体征稳定、心衰减轻,pH值、PaO2和SaO2明显提高(P<0.05);3d后心脏射血分数及运动耐力明显增加(P<0.01)。结论无创双水平气道正压通气通过调节适当吸气压力水平和呼气末正压水平,可改善心功能,减轻肺水肿,迅速提高动脉血氧含量。【Objective】To study the effects of noninvasive bi-level positive airway pressure ventilation （BiPAP） on severe congestive heart failure. 【Methods】26 patients with severe congestive heart failure and poor response to conventional therapy were treated with noninvasive bi-level positive pressure ventilation. Their clinical symptoms, signs, Boston＇s record, two-dimensional color Doppler echocardiogram, blood gas analysis and exercise endurance were monitored. 【Results】 21 patients survived with a success rate of 80.8%. Significant improvements of vital signs, pH, PaO2 and SaO2 could be found（P 〈0.05） after ventilation, and ejection fraction and exereise endurance were improved markedly （P 〈0.01） 3 days after ventilation. 【Conclusion】Noninvasive bi-level positive pressure ventilation can decrease the pulmonary edema, elevate PaO2 and SaO2 and promptly improve heart function.

关 键 词：双水平气道正压通气 充血性心力衰竭 

分 类 号：R563[医药卫生—呼吸系统]