慢性乙型肝炎脾虚证候量表研制初探  

Establishment of Measurement Scale for Spleen Deficiency Syndrome in Chronic Hepatitis B

作　　者：乐敏[1] 黄杏[1] 高月求[1] 

机构地区：[1]上海中医药大学附属曙光医院,上海200021

出　　处：《上海中医药杂志》2008年第3期6-9,共4页Shanghai Journal of Traditional Chinese Medicine

基　　金：上海市重点学科建设项目(Y0302);上海市教育委员会E-研究院建设计划项目(E03008)

摘　　要：目的探索建立慢性乙型肝炎脾虚证候量表的方法。方法通过收集文献中有关慢性乙型肝炎脾虚证的主要证候,结合专家问卷调查结果,形成初始量表;对50例慢性乙型肝炎脾虚证患者进行小样本预调查,以t检验、方差分析、因子分析和相关性检验的方法对调查结果进行条目分析,并对初始量表的条目予以修正,形成慢性乙型肝炎脾虚证候量表;利用量表测试241例慢性乙型肝炎脾虚证患者,从效度、信度、反应度等3个方面评价量表的价值。结果编制出含10个条目的慢性乙型肝炎脾虚证候量表,分为腹胀、纳差、乏力、神疲嗜睡、便溏、衄血6个维度;该量表的周重测信度为0.928,Cronbach'sα系数为0.744,因子分析提取出两个公因子,累计方差贡献率为79.24%;各维度与总分的相关系数均在0.73以上。结论该量表可较好地区分病情程度,较为灵敏地反映中医疗效。Objective To develop a specific scale for the chronic hepatitis B patients with spleen deficiency syndrome. Methods By collecting information on spleen deficiency syndrome of chronic hepatitis B based on related medical literature and enquiring questionnaire, we revise the draft scale by performing a small-scale survey on 50 chronic hepatitis B patients with spleen deficiency. Perform a test on 241 chronic hepatitis B patients with spleen deficiency and evaluate the scale from the perspectives of validity, reliability and responsiveness. All the figures are processed with statistic software SPSS 11.5. Detailed method is as follows： evaluate reliability by using Pearson Correlation and paired t-test, evaluate consistency between items by using Cronbach＇s alpha modulus, validity by using gene analysis, and investigate whether significimt difference exists between two independent samples by using independent sample based t-test. Results Scale for spleen deficiency symptoms of chronic hepatitis B contains 10 items, representing 6 dimensions, which are abdominal distention, bad appetite, tiredness, sleepiness, loose stools, and bleeding from nose and teeth. The test-retest correlation coefficient of the scale is 0.928, which means significant reliability exists between results of two tests. Cronbach＇s α of the scale is 0.744, which means items are consistent with each other. Two public factors are extracted from factor analysis while cumulative variance is 79.24%. Conclusion The measurement scale for spleen deficiency of chronic severe hepatitis B is reliable, effective and sensitive, and can be used to assess the curative effects in Chinese medicine.

关 键 词：慢性乙型肝炎 脾虚证 量表 信度 效度 

分 类 号：R259[医药卫生—中西医结合]