综合ICU脓毒症患者临床特征回顾分析  

Retrospective analysis of clinical characteristics of septic cases in general intensive care unit

作　　者：张振辉[1] 陈晓辉[1] 林珮仪[1] 江慧琳[1] 熊旭明[1] 张弋[1] 

机构地区：[1]广州医学院第二附属医院危重病学科,510260

出　　处：《中国急救医学》2008年第3期212-214,共3页Chinese Journal of Critical Care Medicine

摘　　要：目的探讨综合重症监护病房（ICU）脓毒症患者的发病情况。方法回顾分析2005—01～2006—12我院综合ICU入住病例912例，比较重症脓毒症、脓毒性休克和非脓毒症病例的临床特点，分析脓毒症主要的原发感染部位。结果重症脓毒症和脓毒性休克患者平均年龄、APACHE1／评分、呼吸机治疗率、ICU住院时间和病死率均较非脓毒症患者高（P〈0．01）；重症脓毒症患者年龄和APACHE Ⅱ评分与病死率呈正相关；呼吸道感染所致脓毒症患者的病死率较高，与其他部位比较差异有统计学意义（P〈0．01）。结论脓毒症在综合ICU是一种常见病，重症脓毒症患者具有平均年龄大、病情重及病死率高的临床特点，呼吸道感染所致脓毒症比例高，严重影响患者预后。Objective To study the clinical characteristics of septic patients in general intensive care unit. Methods To retrospectively analyze clinical data of 912 cases with sepsis admitted to the ICU of our hospital during 2005 -2006, and to compare clinical characteristics of patients with severe sepsis, septic shock and non - sepsis. In addition, the site of primary infections in the patients with sepsis were investigated. Results There were significant differences in average age, the length in ICU, APACHE Ⅱ scores, the usage frequency of ventilator and mortality between patients with severe sepsis or septic shock and non -sepsis （P 〈 0.01 ） ; There was positive correlation between age, APACHE Ⅱ score and mortality in the patients with severe sepsis ; Compared with other causes, the mortality of sepsis as a result of infection from respiratory system showed a significant difference （ P 〈 0.01 ）. Conclusions Sepsis occurs generally in the ICU, especially clinical characteristics such as old age, severity of illness and higher mortality in patients with severe sepsis is evident ; The proportion is high for patients with sepsis as a result of infection from respiratory system,which affects the prognosis of patients.

关 键 词：脓毒症 重症脓毒症 脓毒性休克 临床特征 综合重症监护病房 

分 类 号：R459.7[医药卫生—急诊医学]