早期高血压肱动脉血管内皮功能研究  

Evaluation of brachial artery endothel ial function in early-stage hypertension

作　　者：谢伟[1] 刘俊明[1] 黄文军[1] 李辉[1] 李科[1] 

机构地区：[1]新疆兵团医院心内科,新疆乌鲁木齐830002

出　　处：《新疆医科大学学报》2008年第3期275-276,共2页Journal of Xinjiang Medical University

摘　　要：目的:探讨早期高血压患者血管内皮功能变化。方法:选择40例早期高血压患者与40例正常对照者,应用高分辨率超声检测肱动脉充血性反应和含服硝酸甘油后内径和峰值流速变化。结果:早期高血压患者肱动脉充血性反应后内径和峰值流速的变化率明显低于对照组,而含服硝酸甘油后的变化率与正常对照组无明显差别。结论:早期高血压肱动脉内皮依赖性舒张功能减低,并可以被高分辨率超声检测。Objective., To explore endothelial function in early-stage hypertension, Methods： Diameter and peak velocity of brachial artery of 40 patients with early-stage hypertension and 40 age-gender-matched normal control subjects were measured by high resolution ultrasonography at basal and hyperemic condition and after taking nitroglycerin, Results： The increased percentage of the brachial artery diameter and peak velocity at hyperemic condition was lower in patients with hypertension than that in normal control subjects, There was no significant difference between changes in the two groups in response to nitroglycer- in. Conclusion： Endothelial function impairment of brachial artery appears in early-stage hypertension and can be detected by high resolution ultrasonography.

关 键 词：高血压 肱动脉 血管内皮功能 

分 类 号：R544.1[医药卫生—心血管疾病]