补骨生髓胶囊治疗肾阳虚证原发性骨质疏松症的临床研究  

Clinical Study of Bugu Shengsui Capsule in Treating Primary Osteoporosis with Kidney-Yang Deficiency Syndrome

作　　者：谢雁鸣[1] 张方直[1] 周文泉[1] 高普[1] 傅仁杰[1] 赵天予[1] 李承军[1] 

机构地区：[1]中国中医研究院西苑医院,中日友好医院,中国中医研究研究广安门医院基础室

出　　处：《中国中西医结合杂志》1997年第9期526-530,共5页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：国家中医药管理局青年基金

摘　　要：目的：评价补肾法治疗肾阳虚证的原发性骨质疏松症的临床效果。方法：采用补骨生髓胶囊治疗８０例该病患者，并用美国Ｌｕｎａｒ公司ＤＰＸ－Ｌ型双能Ｘ线有关指标仪及放射免疫法等检测治疗前后有关指标。结果：补骨生髓胶囊临床显效率及总有效率分别为４６％和８２％，其疗效明显高于对照组（维生素Ｄ加钙剂）。经双能Ｘ线骨密度（ＤＥＸＡ）证实，补骨生髓胶囊能明显提高原发性骨质疏松症患者的骨密度。该药还能提高降钙素、促黄体生成素及血钙水平和降低甲状旁腺素水平。结论：补肾法治疗原发性骨质疏松的作用是通过提高患者的骨密度，抑制骨吸收，减少骨量丢失等环节实现的。To assess the effect of Bugu Shengsui capsule (BGSSC) in treating primary osteoporosis. Meththe:Using double energy X-ray bone densimeter and radioimmunoassay (RIA), the effect of BGSSC in treating primaryosteoporosis (OP) with Kidney-Yang Deficiency syndrome. Results: The clinical markedly effective and total effective rates of BGSSC were 46% and 82%, respectively. The rate of TCM group is significantly higher than that ofthe control group (Vitamin D plus calcium). BGSSC could improve bone mineral density by the verification of double energy X-ray bone dansity(DEXA). It could also increase the level of serum calcitonin, luteinizing home andcalcium, decrease the activity of parathyroid hormone. Conclusions: The effects of BGSSC on primary OP includedincreasing patient's bone mineral density, depressing bone resorption and decreaSing bone loss.

关 键 词：补骨生髓胶囊 原发性 骨质疏松 中医药疗法 

分 类 号：R274.911[医药卫生—中西医结合]