320例急性肾功能衰竭患者的临床分析  

Clinical analysis of 320 cases with acute renal failure

作　　者：李军辉[1] 汪年松[1] 王锋[1] 

机构地区：[1]上海交通大学附属第六人民医院肾内科,200233

出　　处：《中华肾脏病杂志》2008年第3期154-157,共4页Chinese Journal of Nephrology

基　　金：上海市自然科学基金（05ZRl4086）;上海市卫生局重点攻关课题（2003ZD01）;上海市卫生局课题（034044）

摘　　要：目的探讨急性肾功能衰竭（ARF）住院患者的病因、预后及影响预后的因素。方法回顾性研究我院2003年12月至2006年12月期间急性肾功能衰竭患者的临床资料。结果观察期间住院患者共108744例次，其中ARF患者320例，老年ARF患者135例，占42．2％。ARF主要病因为感染、心力衰竭和药物。ARF患者总体病死率为31．9％，老年人病死率较高。Logistic回归分析显示心力衰竭、呼吸衰竭及恶性肿瘤是与预后相关的危险因素。接受肾替代治疗组患者病死率低于保守治疗组（23．2％比35．6％，P〈0．05）。结论住院患者中ARF的发生率、病死率高，替代治疗组预后较好。Objective To investigate the cause, prognosis and risk factors of hospitalized patients with acute renal failure （ARF）. Methods The clinical data of patients with ARF in our hospital from December 2003 to December 2006 were studied retrospectively. Results There were 108 744 admissions during the study period and 320 met with the diagnostic criteria of ARF. Of 320 ARF patients, 135 （42.2%） were indentified with the onset of the disease over or at the age of 60. Infection, heart failure and drug were the major causes of ARF. The overall mortality rate of ARF patients was 31.9%. The mortality rate of the elderly was significantly higher than that of the non-elderly. The Logistic regression analysis revealed that heart failure, respiratory failure and malignant tumor were the related risk factors of prognosis. The mortality in replacement therapy group was lower than that in conservative treatment group （23.2% vs 35.6%, P〈0.05）. Conclusions The incidence and mortality of hospitalized patients with acute renal failure are high. The prognosis of replacement therapy group is better than conservative treatment group.

关 键 词：肾功能衰竭 急性 病死率 住院 

分 类 号：R692.5[医药卫生—泌尿科学] R587.1[医药卫生—外科学]