应用定量组织速度及应变率成像评价2型糖尿病患者左心室舒张功能  

Evaluation of left ventricular diastolic function by quantitative tissue velocity and strain rate imaging in the patients with type 2 diabetes

作　　者：项娟娟[1] 张军[1] 朱永胜[1] 周晓东[1] 李军[1] 

机构地区：[1]第四军医大学西京医院超声诊断科,陕西西安710032

出　　处：《中国医学影像技术》2008年第3期378-381,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨定量组织速度及应变率成像技术在2型糖尿病患者左心室舒张功能中的应用价值。方法42例行冠状动脉造影证实冠脉狭窄率≤50%的2型糖尿病患者,分为血压正常的单纯糖尿病组(DM20例)和糖尿病合并高血压组(DM+HT22例)。设25例年龄、性别相匹配的健康志愿者为正常对照组(NC)。在静息状态下,应用定量组织速度和应变率成像技术,分别于左心室各室壁二尖瓣环及不同节段测量并比较各组舒张期二尖瓣环运动速度(Ea、Aa)、室壁不同节段长轴方向心肌的运动速度(Em、Am)及其峰值应变率(SRe、SRa),同时与常规超声心动图相对比。结果两组糖尿病患者Ea、Ea/Aa、E/Ea与正常对照组相比有显著差异。两组糖尿病患者室壁不同节段SRe均明显低于正常对照组(P<0.05)。结论应用定量组织速度和应变率成像技术,能够在静息状态下检测2型糖尿病患者左心室舒张功能早期受损情况,有助于糖尿病心肌病的早期诊断。Objective To investigate the clinical application of quantitative tissue velocity and strain rate imaging in the evaluation of left ventricular diastolic function in patients with type 2 diabetes. Methods Forty-two patients with type 2 diabetics who had no evidence of coronary artery disease by coronary angiography and 25 age- and sex-matched normal controls （NC） were enrolled. The diabetes patients were divided into normal blood pressure group （DM, n= 20） and hypertension group （DM＋ HT, n= 22）. All the patients underwent Doppler echocardiography at rest. Early diastolic peak velocity of the mitral annulus and long axis myocardial peak strain rates of left ventricle segment together with parameters of mitral inflow profile were measured with quantitative tissue velocity and strain rate imaging. Results There were significant differences between the two diabetic groups and the control group in the Ea、Ea/Aa、E/Ea, but the two diabetic groups had much lower SRe in different ventricular segments than the control group （P〈0.05）. Conclusion The strain rate and tissue Doppler imaging could detect the early impairment of heart diastolic function in the patients with diabetes at rest, contributing to the early diagnosis of diabetes cardiomyopathy.

关 键 词：糖尿病 超声心动描记数 应变率成像 定量组织速度成像 舒张功能 

分 类 号：R587.1[医药卫生—内分泌] R445.1[医药卫生—内科学]