鼻咽癌易感基因研究中自愿者知情同意调查报告  

The investigation of volunteers informed consent in project on nasopharyngeal carcinoma genetic research

作　　者：龙碧霄 梁艳芳[1] 蔡永林[1] 郭秀婵[2] 

机构地区：[1]梧州市红十字会医院,广西梧州543002 [2]中国疾病预防控制中心病毒病预防控制所

出　　处：《中国医学文摘（肿瘤学）》2008年第1期87-88,94,共3页Journal of Chinese Medical Abstracts·Oncology

基　　金：国家自然科学基金资助项目（30672377）

摘　　要：目的通过对鼻咽癌易感基因研究受试者的知情同意情况，体现科学研究中知情同意权的重要性．方法：采集研究所需血液标本前向每一位自愿者详细介绍本研究的目的、意义、自愿者参与研究的步骤、标本采集的方法、受试者权利与利益、风险与不适、研究的保密性；自愿者同意后签字确认，同时研究人员签字后方可采集标本。结果。905例鼻咽癌患者有884人自愿参与本研究，即97．7％的患者同意；386人EB病毒IgA／VCA阳性者全部同意；739健康人有713人同意，自愿参与率为96．5％．结论：受试者在知情的前提下，同时权益受到保护，而研究本身对其又无伤害的情况下，绝大多数能支持配合医学科学研究。Objective：To investigate the volunteer＇s informed consent in genetic study on nasopharyngeal carcinoma （NPC）, and reflects the importance of the right to informed consent in scientific research. Methods.. Before the sample collection, explain the goal, meaning, procedure of the research, confidentiality, as well as the risk and benefit to each donor. The donors need sign the consent for confirmation, at meantime the investigator need sign too. Results：About 98% of NPC patients （884 of 905）, all 386 subjects with IgA/VCA antibody positive to EB virus and 96.5% of healthy control （713 of 739） were volunteers to participate this study. Conclusion.. Most people would like to support the science research after been informed, their rights are protected, and no harm to their own.

关 键 词：鼻咽癌 遗传研究 知情同意 调查报告 

分 类 号：R197.32[医药卫生—卫生事业管理] R739.63[医药卫生—公共卫生与预防医学]