中国人群青壮年猝死综合征的流行现状——广东省东莞市、深圳龙岗区及宝安区青壮年猝死综合征的流行病学调查  

The current epidemic circumstance of sudden unexplained nocturnal death syndrome in Chinese——The epidemiological study of sudden unexplained nocturnal death syndrome in Dongguan,Longgang and Baoan District

作　　者：成建定[1] 利焕祥 李杰 卢次勇[3] 唐双柏[1] 周峰[1] 邢浩伟[1] 

机构地区：[1]中山大学中山医学院法医学系,广东广州510080 [2]广东省东莞市公安局刑事科学技术研究所,广东东莞523008 [3]中山大学公共卫生学院流行病学教研室,广东广州510080

出　　处：《国际内科学杂志》2008年第3期125-128,158,共5页International Journal of Internal Medicine

基　　金：国家自然科学基金项目(30500581);广东省自然科学基金项目(05001685)

摘　　要：目的了解中国人群不明原因夜间睡眠猝死综合征（SUNDS）的流行现状。方法采用描述性研究方法，对广东省东莞市、深圳市宝安区及龙岗区975例SUNDS案件资料进行回顾性分析。结果中国人SUNDS主要发生于劳动强度较高、文化素质较低的生产作业工人，年发病率约为1．0人／10万；男性病例占93．23％，80．56％的病例集中在21—40岁；4、5月份异常高发，SUNDS病例与急诊发热病例的月份分布呈正相关（r=0．785，P〈0．05）；64．96％的病例籍贯属于北纬30度以南地区；目击病例的临床症状集中表现为睡眠中突发呼吸障碍。结论本研究首次勾勒了中国人群SUNDS的流行现状并初步提出与其发生可能相关的危险因素，为后继的病因探索奠定了基础。Objective To investigate the current epidemic circumstance of sudden unexplained nocturnal death syndrome（SUNDS） in Chinese. Methods The autopsy data of 975 SUNDS cases in city of Dongguan, districts of Longgang and Baoan were studied retrospectively with epidemiologic description. Results SUNDS mainly took place in workers with high labor intensity and poor education. The yearly incidence rate was about 1.0 per 100 000 persons. The male victims occupied 93.23% of all cases. The age of 80. 56% cases ranged from 21 to 40 years old and the peak months of SUNDS occurrence were April and May. The monthly distribution of SUNDS cases was positively correlated with that of emergency fever cases（ r = 0. 785 ,P 〈 0.05 ）. 64.96% eases come from district on the south of 30 degrees north latitude. The clinical manifestation of cases with witness were focused on abrupt hypnic abnormalities during nocturnal sleep. Conclusion The epidemiologic circum- stance of SUNDS in Chinese was firstly outlined and some possible risk factors were preliminary put forward.

关 键 词：青壮年猝死综合征 发热 病因学 流行病学 

分 类 号：R541[医药卫生—心血管疾病]