基层医院癌痛患者使用麻醉性止痛药的调查分析与探讨  

Analysis and Evaluation on the Effect of Narcotic Drug in the Treatment for Patients with Severe Cancer Pain

作　　者：黄凯文[1] 吴伟文[1] 吴淑敏[2] 

机构地区：[1]广东省佛山市顺德区第一人民医院药剂科,广东佛山528300 [2]广东药学院

出　　处：《今日药学》2008年第1期11-15,共5页Pharmacy Today

摘　　要：目的评估我院2006年门诊中晚期癌痛患者麻醉药品的应用情况,了解患者的用药效果,为临床合理用药提供参考依据。方法利用限定日剂量(DDD)与药物利用指数(DUI)为指标,对门诊麻醉药品处方共692张进行回顾性分析,并对部分患者进行电话调查其用药情况。结果用于中晚期癌症止痛的麻醉药品共10种,其中用药频度及用量最大的均是硫酸吗啡缓释片。电话追踪调查发现,多数患者疼痛缓解不满意,其生命终末期生活质量较差。结论我院癌痛治疗基本符合三阶梯止痛原则,但仍存在一定的问题,有待于完善。Objective To evaluate the application and effect of narcotic drug in treatment of severe cancer pain in our hospital, in order to provide a reference for rational clinical drug usage. Methods 692 prescriptions of narcotic drugs from those written out at OPD in 2006 were analyzed retrospectively, by taking defined daily doses （DDD） and drug utilization index （DUI） as indices. Results Ten kinds of narcotic drugs were used. Among these narcotics examined, the Morphine Sulfate Sustained-release tablet ranked first for its largest amount of prescription, highest frequency of use and maximum of the DDDs. A majority of cancer patients were not satisfied with the relieving effect of pain, and had bad quality of life in last vital stage. Conclusion The Three Ladder Aeesodyne Medication in patients with cancer in our hospital was fundamentally rational, but there are still some problems that should be solved.

关 键 词：癌痛 麻醉药品 药物利用 癌症三级止痛阶梯疗法 

分 类 号：R971.2[医药卫生—药品]