喹啉取代咔唑化合物的合成  

Synthesis of Quinolinyl-substituted Carbazole Derivatives

作　　者：韩艳淑[1] 刘文恒[1] 刘乾才[1] 

机构地区：[1]华东师范大学化学系,上海200062

出　　处：《合成化学》2008年第2期203-206,共4页Chinese Journal of Synthetic Chemistry

基　　金：教育部留学回国人员基金资助项目(2004-527)

摘　　要：以咔唑为原料,通过乙酰化反应合成了2-乙酰基咔唑(2)和3,6-二乙酰基咔唑(5);2和5分别与2-氨基二苯甲酮衍生物在酸催化下通过典型的Fried laender环化反应合成了一系列新的2-(4-取代苯基)喹啉咔唑和3,6-二(4-取代苯基)喹啉咔唑,其结构经1H NMR,IR和元素分析表征。A series of new quinolinyl-substituted carbazole derivatives, 2-（4-phenyl quinolyl）carbazole and 3,6-bis[2-（4-phenylquinolinyl） ] carbazole, were synthesized from 2-acetylcarbazole（2） and 3,6-diacetyl carbazole（5） by Friedlaender condensation in the presence of acid. 2 and 5 were obtained by acylation reaction from carbazole. The structures were comfirmed by ^1H NMR, IR and elemental analysis.

关 键 词：咔唑 喹啉 合成 Friedlander环合 

分 类 号：O625.15[理学—有机化学] O623.32[理学—化学]