抗敏颗粒质量标准研究  

Study on Quality Standards of Kangmin Granule

作　　者：冯琳[1] 李瑞海[1] 

机构地区：[1]辽宁中医药大学,辽宁沈阳110032

出　　处：《中国中医药杂志》2008年第3期6-9,共4页

摘　　要：目的：建立抗敏颗粒荆的质量标准。方法：采用薄层色谱法对抗敏颗粒荆中的当归、桂枝进行薄层色谱鉴别；采用高效液相色谱法对黄芩中的黄芩苷的含量进行测定。结果显示：试验采用薄层色谱法定性鉴别．色谱斑点清晰，分离度良好，阴性液无干扰；以HPLC法测定本品黄芩中的黄芩苷的含量，方法精密度、稳定性、重复性良好，回收率在98．1～100．6％之间，RSD为1．5％。结论：本试验所确定的质量分析方法稳定可靠，能较为合理地对处方中各组分进行定性、定量检测，重复性强，可作为抗敏颗粒的质量标准。Object：To establish the quality control method for Kangmin granule. Methods：Radix angelicae sinensis and Ramulus cinnamomi was identified by TLC;and the content of Baicalin were determined by HPLC. Result shows：the spots on the TLC are clear, The determination of Baicalin showed a good linear relationship at arrange of from 0.0944 to 0.9440μ g, the average recoveries of Baicalin was from 98.1 to 100.6%,RSD was 1.50%.Conclusion： the qualitative and quantitative analytic methods are stable, reliable and easy to repeat. It can be applied as the standard of Kangmin Granule.

关 键 词：抗敏颗粒剂 质量标准 薄层鉴别 高效液相色谱法 

分 类 号：R927.11[医药卫生—药学]