经皮冠状动脉介入治疗对心脏自主神经活性长期影响  

The long-term effect of percutaneous coronary intervention on cardiac autonomic nerve system

作　　者：邓昌明[1] 黄晶[1] 刘地川[1] 江永红[1] 朱悫[1] 罗开良[1] 

机构地区：[1]重庆医科大学附属第二医院心血管内科,重庆400010

出　　处：《重庆医科大学学报》2008年第3期352-353,360,共3页Journal of Chongqing Medical University

基　　金：重庆市卫生局科研基金(2005-31);重庆市自然科学基金(CSTC2006BB5280)。

摘　　要：目的:探讨经皮冠状动脉介入(Percutaneous coronary intervention,PCI)治疗后心脏自主神经活性长期动态变化规律,评价PCI对冠心病预后的影响。方法:选择经冠状动脉造影证实并适合PCI的32例冠心病患者,年龄性别匹配的经冠状动脉造影证实的非冠心病患者32例,所有入选者于PCI术前、术后1周、1月、3月、6月及1年进行心率变异(Heart rate variability,HRV)检测。结果:冠心病患者HRV减低,PCI术后1周HRV较术前减低更为明显,术后1月、3月HRV逐步升高,于6月较术前改善最为明显,术后1年几乎达对照组水平。结论:冠心病患者HRV减低,心脏自主神经功能受损,PCI术后短期内心脏自主神经功能进一步受损,但明显改善远期心脏自主神经功能。Objective：To investigate the long effect of percutaneous coronary intervention（PCI） on heart rate variability（HRV） in patients with coronary artery disease（CAD）,and to evaluate the prognosis of patients with CAD receiving PCI. Methods：To choose 32 patients confirmed by coronary arteriography and suitable for PCI,and to choose 32 control patients with non-CAD confirmed by coronary arteriography,HRV indices were analyzed before PCI and lweek,lmonth,3months,6months,lyear after PCI. Results：HRV indices were decreased in patients with CAD, HRV was lower in patients in lweek after PCI than that before PCI,HRV was gradually increased in lmonth and there was significantly improved in 6months after PCI,and nearly to the level of control group in one year. Conclusion：HRV is low in the patients with CAD,there is slightly decreased in the early stage of PCI,but the long effect of PCI on heart rate variability can be observed.

关 键 词：冠状动脉疾病 经皮冠状动脉介入 心率变异 自主神经系统 

分 类 号：R541.4[医药卫生—心血管疾病]