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机构地区:[1]江苏省镇江市第一人民医院儿童医院,江苏镇江212002
出 处:《儿科药学杂志》2008年第2期48-49,共2页Journal of Pediatric Pharmacy
摘 要:目的:观察沙美特罗替卡松治疗儿童中度哮喘的临床疗效。方法:82例中度哮喘患儿随机分为观察组和对照组,分别应用沙美特罗替卡松和布地奈德气雾剂治疗1年,观察两组患儿哮喘急性发作次数及治疗前后肺功能(FEV1和PEF预计值%)的变化。结果:观察组哮喘急性发作次数明显少于对照组;两组均可提高FEV1、PEF预计值%,改善肺功能,但治疗组明显优于对照组。结论:沙美特罗替卡松治疗儿童哮喘的临床疗效较好,可以作为儿童哮喘的首选治疗。Objective: To explore the efficacy of seretide in treating childhood patients with moderate asthma. Methods: Data of 82 asthmatic cases were gathered and randomly divided into two groups. The experimental group was treated with seretide and the control group with budesonide (BUD). The times of acute onset of asthma and Pulmonary Function (FEV1 and PEF) were analyzed statistically. Results: The times of acute onset of asthma was reduced in the experimental group than in the control group. The levels of FEV1 and PEF were increased in both groups. The improvement of Pulmonary Function was found better in the experimental group than in the control group. Conclusions: Therapy with seretide produces better results than other drugs and it was the first choice of therapy for childhood asthma.
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