一种有机硅季铵盐抗菌剂的合成和性能  

Synthesis of a polisilicone quaternary ammonium salt as antibacterial agent and its properties

作　　者：张昌辉[1] 谢瑜[1] 徐旋[1] 赵霞[1] 

机构地区：[1]陕西科技大学化学与化工学院,陕西西安710021

出　　处：《日用化学工业》2008年第2期99-102,共4页China Surfactant Detergent & Cosmetics

基　　金：陕西省教育厅自然科学专项基金资助项目(05JK158);咸阳市科技计划发展项目(XK06010-7)

摘　　要：利用γ-氯丙基三甲氧基硅烷(CTS)与N,N-二甲基十二烷基胺(DDA)反应,合成了N,N-二甲基-N-十二烷基氨丙基三甲氧基硅烷氯化铵(DDATAC)。研究了原料配比、反应温度和溶剂等因素对DDATAC收率的影响。较佳反应条件为:n(CTS)∶n(DDA)=1.0∶1.1,二甲亚砜为溶剂,于120℃反应30 h,DDATAC收率为91.37%。通过红外光谱、元素分析确定产物的化学结构,最后测定了产物的抗菌性能和耐洗性能。结果表明,制备得到的有机硅季铵盐具有良好的抗菌性能和一定的抗菌耐洗性。A quaternary surfactant, N, N - dimethyl - N - dodecylaminopropyltrimethoxy ammonium chloride （DDATAC） was synthesized from T -ehloropropyl trimethoxy silane （CTS） by quaterisation with N, N - dimethyldodeeylamine （DDA）. The effects of raw material composition, reaction temperature and solvent on the yield of DDATAC were studied. The optimal reaction conditions for the synthesis are, molar ratio of CTS to DDA, 1.0： 1.1; reaction medium, dimethyl sulfoxide; reaction temperature, 120℃. The yield of the product achieves 91.37%. The chemical structure of the product was characterized by IR spectrum and elemental analysis. Besides, the antibacterial property and laundry resistance were measured with good performance indicated.

关 键 词：阳离子表面活性剂 N N-二甲基-N-十二烷基氨丙基三甲氧基硅烷氯化铵 合成 抗菌性能 

分 类 号：TQ264.1[化学工程—有机化工]