血脂异常患者甲状腺功能异常患病率的调查  

Prevalence of thyroid dysfunction in patients with dyslipidemia

作　　者：柏林[1] 覃又文[1] 刘翠萍[1] 茅晓东[1] 刘超[1] 

机构地区：[1]南京医科大学第一附属医院内分泌科,南京210029

出　　处：《临床检验杂志》2008年第2期125-126,共2页Chinese Journal of Clinical Laboratory Science

基　　金：江苏省医学重点学科项目(SK200214)

摘　　要：目的调查血脂异常患者甲状腺功能的变化特征,探讨血脂异常与甲状腺功能(TSH、FT3、FT4)相互间的关系。方法调查412例血脂异常患者,男249例,女163例,平均年龄(50.7±15.7)岁,以497例无血脂异常的江苏省居民为对照,男287例,女210例,平均年龄(49.0±13.8)岁。比较两组人群甲状腺功能异常的患病率和其他指标。结果血脂异常组有71例(17.2%)甲状腺功能异常,对照组有56例(11.3%),两组差异有显著性(P=0.001);女性、老年(≥50岁)及HDL-C降低均与血脂异常患者发生甲状腺功能异常相关。结论血脂异常患者甲状腺功能异常患病率较正常人群高,需重视其甲状腺功能的常规检查。Objective To investigate the epidemiological characteristics of thyroid function in dyslipidemia patients of Jiangsu region, and further explore the relationship between dyslipidemia and thyroid function. Methods Four hundred and twelve dyslipidemia patients （ dyslipidemia group ： 163 female and 249 male, mean age ： 50.7 ±15.7 ） and 497 residents without dyslipidemia （ control group ： 210 female and 287 male, mean age ： 49.0 ± 13.8 ） were included in this study. The 2 groups were compared in terms of thyroid dys- function prevalence and other parameters. Results Thyroid dysfunction was found in 71 （ 17.2% ） eases of the dyslipidemia group and in 56 （ 11.2% ） eases of the control group （ P = 0.001 ）. Gender （ female ）, old age （≥ 50 ） and low HDL-C level were associated with thyroid dysfunction. Conclusion The patients with dyslipidemia may more likely suffer from thyroid dysfunction, so thyroid function among these patients should be screened.

关 键 词：血脂异常 甲状腺功能异常 患病率 

分 类 号：R446.1[医药卫生—诊断学]