3种药物治疗甲亢的经济学分析  

Pharmacoeconomics of 3 Drugs in the Treatment of Hyperthyroidism

作　　者：黄际薇[1] 郑琼良[1] 肖珮玉[1] 郑伟峰[1] 

机构地区：[1]中山大学附属第三医院,广州市510630

出　　处：《中国药房》2008年第11期805-807,共3页China Pharmacy

摘　　要：目的:评价3种药物治疗甲亢的经济学效果。方法:将90例甲亢患者分为A、B、C组,分别给予丙硫氧嘧啶片、甲巯咪唑片(国产)、甲巯咪唑片(进口),均治疗28d,观察其疗效和不良反应,并运用成本-效果法进行分析。结果:A、B、C组的平均总成本分别为3947·24、3868·28、3895·72元,有效率分别为83·33%、86·67%、93·33%(P>0·05)。结论:B方案较经济,但综合比较仍是C组方案较佳。OBJECTIVE： To evaluate the cost-effectiveness of 3 drugs in the treatment of Hyperthyroidism. METHODS： A total of 90 patients with hyperthyroidism were assigned to receive Propylthiouracil Tablets （Group A）, domestic Thiamazole Tablets （Group B） or imported Thiamazole Tablets （Group C） for 28d, 28d, and 28d, respectively. The therapeutic effects and the adverse drug reactions of 3 groups were observed, and the cost-effectiveness analysis was carried out. RESULTS： The average total costs of Group A, B and C were 3 947.24 yuan, 3 868.28 yuan and 3 895.72 yuan; the effective rates were 83.33%, 86.67% and 93.33% （P 〉0.05）, respectively. CONCLUSION： Scheme B is the preferable one in cost-effectiveness, however,Scheme C is the best one by comprehensive comparison.

关 键 词：甲亢 治疗方案 最小成本分析 

分 类 号：R977.14[医药卫生—药品] R956[医药卫生—药学]