重症肌无力患者实施规范化护理的临床研究  

Clinical Study on Standardized Nursing for Myasthenia Gravis Patients

作　　者：金真[1] 江淑聘[1] 曾韶凤[1] 

机构地区：[1]广州中医药大学第一附属医院二内科,广东广州510405

出　　处：《广州中医药大学学报》2008年第2期121-123,127,共4页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广州中医药大学邓铁涛基金立项项目(编号:0030005)

摘　　要：【目的】探讨重症肌无力患者规范化护理的效果。【方法】将102例重症肌无力患者随机分为规范化护理组(A,N=52例)和传统护理组(B,N=50例),两组在相同治疗措施的基础上,分别实施规范化护理和传统护理,比较两组危象发生率、上机率和并发症发生率,比较两组脱机时间和生存质量评价结果。【结果】(1)两组在危象发生率、上机率和并发症发生率方面差异均无显著性意义(P>0.05),但传统护理组的上述指标发生率有高于规范化护理组的趋势。(2)规范化护理组的脱机时间比传统护理组明显缩短,两组比较,差异有显著性意义(P<0.05)。(3)两组SF-36健康状况量表评价结果显示,两组入院时8个维度分别比较,差异均无显著性意义(P>0.05);出院时,两组8个维度均较入院时有所改善(P<0.05或P<0.01),且规范化护理组在生理职能(RP)、一般健康状况(GH)、社会功能(SF)、情感职能(RE)和精神状态(MH)方面明显高于传统护理组,差异有显著性意义(P<0.05或P<0.01),而在身体疼痛(BP)、精力(VT)和生理机能(PF)等方面两组差异无显著性意义(P>0.05)。【结论】规范化护理能提高重症肌无力患者的临床疗效,减少重症肌无力危象和并发症的发生,提高患者的生存质量。Objective To observe the effect of standardized nursing for myasthenia gravis（MG） patients.Methods One hundred and two MG patients were randomized into two groups.Based on the same treatment,group A（N=52） received standardized nursing and group B（N=50） received traditional nursing.The MG crisis incidence,frequency of using ventilator and the complication incidence as well as the time of weaning from mechanical ventilation,and quality of life（QOL） were compared in the two groups.Results（1） The differences of MG crisis incidence,frequency of using ventilator and the complication incidence were insignificant between the two groups（P〉0.05）.There existed a increased trend of the above parameters in group B.（2） Time of weaning from mechanical ventilation was shortened in group A than that in group B（P〈0.05）.（3） The results of quality of life evaluation by SF-36 showed that the differences of the 8 dimensions of SF-36 were insignificant at admission in the two groups（P〉0.05）,but were significant（P〈0.05 or P〈0.01） when leaving hospital.When leaving hospital,the scores of role function physical（RP）,general health（GH）,social function（SF）,role function emotional（RE）,and mental health（MH） were higher in group A than those in group B（P〈0.05 or P〈0.01）,but the differences of physical function（PF）,bodily pain（BP）,vitality（VT） were insignificant in the two groups（P〉0.05）.Conclusion Standardized nursing can increase the therapeutic effect on MG by reducing MG crisis and complication incidence,and improving quality of life of MG patients.

关 键 词：重症肌无力 规范化护理 

分 类 号：R473.5[医药卫生—护理学]