大气污染与疾病关系的相关及广义估计方程分析  

Analysis of Correlation and Generalized Estimating Equation for the Relationship between Atmospheric Pollution and Diseases

作　　者：黄欣欣[1] 洪荣涛[2] 周天枢[2] 戴龙[3] 蔡琳[1] 

机构地区：[1]福建医科大学公共卫生学院,福州350004 [2]福建省疾病预防控制中心 [3]厦门市疾病预防控制中心

出　　处：《中国预防医学杂志》2008年第2期96-99,共4页Chinese Preventive Medicine

基　　金：福建省重点高校建设项目(XZ04006);福建省科技开发计划项目(2005D075);全国优秀博士学位论文专项资金资助(200157)

摘　　要：目的探讨厦门市大气污染物浓度与疾病死亡率的关系。方法采用相关和广义估计方程,对1987-2001年厦门市大气污染物年均监测浓度与疾病标化死亡率资料进行分析。结果大气污染指数与慢性阻塞性肺疾病(COPD)、恶性肿瘤、肺癌、心脏病的标化死亡率呈正相关,SO2、总悬浮颗粒物(TSP)与脑血管疾病和肺癌标化死亡率呈正相关,慢性阻塞性肺疾病、恶性肿瘤和心脏病标化死亡率与SO2、TSP和降尘浓度呈正相关,广义估计方程回归系数显著(P<0.05)。结论大气污染物与多种疾病有关联。Objective To study the relationship between atmospheric pollutant concentration and death rate of diseases in Xiamen City. Methods Methods of correhfion and generalized estimating equation （GEE） were used to analyze the data of the standardized mortality ratio of diseases and annual mean monitoring concentration of atmospheric pollutant in Xiamen City from 1987 to 2001. Results The air pollution parameter had positive correlations with the standardized mortality ratios of chronic obstructive pulmonary diseases, malignancy, lung cancer and cardiac diseases.The standardized mortality ratios of cerebrovascular disease and lung cancer had positive correlations with the concentrations of SO2, total suspended particulates （TSP）. The concentrations of SO2, TSP and dust fall had positive correlations with the standardized mortality ratios of chronic obstructive pulmonary diseases, malignancy and cardiac diseases. The regression coefficients of GEE were statistically significant （P 〈 0.05）. Conclusion The atmospheric pollutant concentration was associated with various diseases.

关 键 词：大气污染 疾病标化死亡率 广义估计方程 

分 类 号：X503[环境科学与工程—环境工程]