乳腺组织的位相衬度成像  

Phase-contrast Imaging of Breast Tissues

作　　者：刘成林[1] 张新夷[2] 

机构地区：[1]盐城师范学院物理系,江苏盐城224002 [2]复旦大学同步辐射研究中心,上海200433

出　　处：《河北理工大学学报（自然科学版）》2008年第2期92-95,99,共5页Journal of Hebei Polytechnic University:Social Science Edition

基　　金：江苏省高校自然科学基础研究项目(06KJD140199);国家重点基础研究专项973项目(2005CB523306)资助

摘　　要：将位相村度成像用于乳腺肿瘤的结构研究后,发现:正常乳腺组织的吸收图像的清晰度比较高,原因是正常乳腺组织比较致密,对于对X射线的吸收相对较强。而位相衬度成像在分辨肿瘤组织内部结构方面的优势是比较明显的,能够清晰地显示出乳腺组织中的一些精细结构,并可以反映出正常组织、良性肿瘤组织和癌变组织结构的特异性。在位相衬度成像中,图像的村度是与样品到探测器的距离有关的,在不同样品到探测器的距离下,位相村度成像的分辨率是不同的。根据衬度传递函数(CTF),可以估计出乳腺癌组织中的钙化尺度在30μm左右。The phase-contrast imaging is used to study the structures of breast tissues. The absorption image of normal breast tissue has better definition than that of phase-contrast image because the normal breast tissues are compact,and the absorption of X-ray is very. intensive. However,the superiorhy of phase-contrast imaging is obvious in the tissues of tumor. Some microstructures, which can reflect the differences of normal, benign and malignant breast tissues,are distinctly stlown in phase-contrast images. The contrast of image,and the resolving power as well, are related to the distance from the sample to the delector in phase-contrast imaging. According to the contrast transfer function,the sizes of micro-calcifications are estimated to be approximately 30μm in breast cancer tissues.

关 键 词：位相衬度成像 乳腺组织 同步辐射 

分 类 号：O434.1[机械工程—光学工程] R817[理学—光学]