猫背根神经节中C和A_δ类传入细胞的SP和CGRP观察  

SP AND CGRP IN ELECTROPHYSIOLOGICAL IDENTIFIED CAND A_δ-FIBER NEURONS OF THE DORSAL ROOT GANGLIA OF CATS IN VIVO

作　　者：陶元祥[1] 舒友生[1] 王过渡[1] 赵志奇[1] 

机构地区：[1]中国科学院上海脑研究所,上海200031

出　　处：《神经解剖学杂志》1997年第1期15-18,共4页Chinese Journal of Neuroanatomy

摘　　要：本交通过细胞内电生理记录结合胞内注射LuciferYellow（LY）和免疫细胞化学方法，对猫背根神经节中C和Aδ类传入神经细胞的SP和CGRP的存在状态进行了观察．结果发现43．75％C类传入细胞和16．67％Aδ传入细胞是SP样免疫反应阳性；57.64％C类传入细胞和15．38Aδ类传入细胞是CGRP样免疫反应阳性．表明SP和CGRP与C和Aδ类传入纤维相关，为其活性物质，可能参与外周伤害性信息向脊髓的传递。In the dorsal root ganglia of cats, SP and CGRP in the neuronal somata of single C- and Aa- fibers were observed in vivo using a combination of intracellular electrophysiological recording an`] Lucifer YeIIow inkction with immunocy tochemistry. The results showed that seven of the sixteen C-fiber cells and one of the six Aa-fiber cells were SP-like immunoreactive , and eight of the fourteen C-fiber cells and two of the thirteen A8-fiber cells were CGRP-like irnmunoreactive.our results indicated that there was a clear relationship between C-and Aδ-fibers and SP or CGPR, suggesting that SP and CGRP might be involved in the transmission of noxious in formation from periphery to spinal cord.

关 键 词：传入纤维 背根神经节 P物质 降钙素基因 相关肽 

分 类 号：R322.85[医药卫生—人体解剖和组织胚胎学]