慢性前列腺炎患者细菌和支原体感染及耐药性监测  

Detection and antibiotic susceptibility test of the bacteria and mycoplasma in patients with chronic prostatitis

作　　者：刘淑梅[1] 刘春英[2] 李俊平[2] 

机构地区：[1]首都医科大学附属复兴医院,北京100038 [2]石家庄市第二医院,石家庄050051

出　　处：《生殖医学杂志》2008年第2期109-113,共5页Journal of Reproductive Medicine

摘　　要：目的探讨慢性前列腺炎(CP)患者前列腺液中细菌及支原体感染情况,并进行耐药性监测。方法收集CP患者前列腺液标本进行细菌和支原体的培养、鉴定和药物敏感试验,对结果进行统计学分析。结果1,870例患者的前列腺液标本中,培养出革兰阳性球菌1,178株、革兰阴性杆菌112株、支原体954株;革兰阳性球菌以金黄色葡萄球菌为主,万古霉素对其有效;革兰阴性杆菌以大肠埃希菌为主,头孢曲松对其有效;支原体对克拉霉素、罗红霉素敏感,对其他抗菌药物表现出不同程度的耐药。结论金黄色葡萄球菌、表皮葡萄球菌、大肠埃希菌等细菌以及解脲支原体、人型支原体是CP的主要病原体,对抗菌药物呈现不同程度耐药,故对CP应在药敏试验指导下选用敏感性抗菌药物治疗。Objectives： To study the infection of the bacteria and mycoplasma in EPS （expressed prostatic secretion） of patients with chronic prostatitis, and provide clinicians with the results of antibiotic susceptibility test as a guide for drug use. Methods： Bacteria and mycoplasma were isolated and identified, and antibiotic susceptibility tests were done. The results were statistically analyzed. Results： In 1,870 specimens of EPS, there were 1,178 strains of Gram-positive and 112 strains of Gram-negative bacteria, and 954 strains of mycoplasma. Staphylococcus aureus were the most common Gram-positive bacteria and sensitive to vancomycin. Escherichia coli were the most common Gram-negative bacteria and sensitive to ceftriaxone. Mycoplasma strains were susceptible to clarithromycin, roxithromycin, but showed different degrees of resistance to other drugs. Conclusions： Bacteria （Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli etc. ） and mycoplasma（U, urealyticum and M. hominiss）are the possible pathogens in chronic prostatitis. In the treatment of chronic prostatitis, sensitive antibacterials should be selected with the guidance of drug sensitivity test.

关 键 词：慢性前列腺炎 细菌感染 支原体 药物敏感试验 

分 类 号：R697[医药卫生—泌尿科学]