苯海拉明致过敏性休克临床分析及预防对策  

Clinical Analysis of Diphenhydramine-Induced Allergic Shock and Preventive Countermeasures

作　　者：李玉芝[1] 

机构地区：[1]天津市第一中心医院,300192

出　　处：《职业与健康》2008年第9期907-908,共2页Occupation and Health

摘　　要：目的探讨苯海拉明导致过敏性休克的临床特点及预防对策。方法对4例苯海拉明致过敏性休克患者进行回顾性临床分析。结果用药后立即发生过敏性休克1例,5min内1例,20min2例;3例患者处于昏迷状态,1例处于意识不清、极度烦躁不安状态。经过纠正休克、抗过敏性治疗及对症抢救,1h后均救治成功。结论此为药物的矛盾效应导致过敏性休克。治疗Ⅰ型变态反应性疾病,要重视病人的过敏史,建立用药后观察30min的措施是必要的。[ Objective] To explore the clinical features and preventive countermeasures of allergic shock induced by diphenhydramine. [ Methods] Retrospective clinical analysis was made on 4 patients of diphenhydramine-induced allergic shock. [ Results] One case had allergic shock immediately after the injection, one case had allergic shock in 5 minutes after the injection, two cases in 20 minutes; 3 cases fell into coma; one case was in a condition of unconsciousness and severe dysphoria; through shock reclaim, anti-allergie treatment and proper first aid, all the patients were successfully saved after one hour. [ Conclusion ] It is an allergic shock induced by contradictory effect; to treat type Ⅰ metamorphism diseases, the allergic history of the patients should be emphasized; it is necessary to establish the measure of 30 minutes＇observation after giving medicine to the patients.

关 键 词：苯海拉明 过敏 分析 预防对策 

分 类 号：R453[医药卫生—治疗学]