妊娠期糖尿病诊断标准与妊娠结局分析  

Analysis of diagnostic criteria for gestational diabetes mellitus and pregnancy outcome

作　　者：王志群[1] 武巧珍[1] 胡娅莉[1] 陈建琴[1] 孙凤英[1] 许碧云[1] 

机构地区：[1]南京大学医学院附属鼓楼医院妇产科,210008

出　　处：《江苏医药》2008年第4期354-356,共3页Jiangsu Medical Journal

摘　　要：目的探讨不同妊娠期糖尿病（GDM）诊断标准对不良妊娠结局的预测力。方法前瞻性随访2006年4～9月南京鼓楼医院初建大卡并住院分娩的903例孕妇的糖代谢状况和妊娠结局，分析比较美国国家糖尿病数据组（National Diabetes Data Group，NDDG）、美国糖尿病协会（American Diabetes Association，ADA）、教科书（乐杰）、日本和世界卫生组织（World Health Organization，WHO）等不同GDM诊断标准诊断与GDM患者的妊娠结局。结果不同GDM诊断标准的GDM检出率1．66％～9．63％不等，差异有统计学意义（P〈0．01）。除巨大儿的发病率外，不同诊断标准的GDM组的不良妊娠结局与正常组相比，差异无统计学意义（P〉0．05）。结论南京地区GDM对妊娠结局的不良影响主要表现在巨大儿及其相关损害上。为减少巨大儿及其并发症对母婴的伤害，以选择较宽的GDM的诊断标准（如ADA标准）为宜。Objective To analyze the effect of five different diagnostic criteria for gestational diabetes mellitus（GDM） on pregnancy outcome in Nanjing district. Methods Nine hundred and three subjects were collected at Drum Tower Hospital from April to Sept in 2006. The pregnancy outcomes derived from different diagnosing criteria（NDDG, ADA,WHO） were analyzed. Results The incidence of GDM diagnosed with the different criteria was different from 1.66% to 9.63% （P〈0. 01）. The main poor outcome of pregnancy of GDM was macrosomia. No other poor outcome was seen in this group. Conclusions Marosomia is a main poor outcome during pregnancy with GDM and a lenient diagnostic criterion, such as ADA, is suggested to be used for reducing poor outcomes of pregnancy.

关 键 词：妊娠期糖尿病 诊断标准 

分 类 号：R714[医药卫生—妇产科学]