Synthesis and Crystal Structure of 3,3-Dimethyl-7,11-di(thiophene-2-yl)-2,4-dioxyspiro[5. 5]undecane-1,5,9-trione  

作　　者：史达清 杨芳 倪赛男 王香善 

机构地区：[1]College of Chemistry and Chemical Engineering, Key Laboratory of Organic Synthesis of Jiangsu Province, Suzhou University [2]Department of Chemistry, Xuzhou Normal University

出　　处：《Chinese Journal of Structural Chemistry》2008年第4期477-480,共4页结构化学（英文）

基　　金：Supported by the Foundation of the Key Laboratory of Biotechnology for Medical Plants of Jiangsu Province (No. 02AXL13)

摘　　要：The title compound （C19H18O5S2） has been synthesized by the reaction of thio- phene-2-carboxaldehyde, isopropylidene malonate and 4-chloroaniline using [bmim]Br as solvent, and characterized by IR, ^1H NMR and X-ray single-crystal diffraction. The crystal belongs to monoclinic, space group P21/n with a = 9.4872（15）, b = 9.5148（13）, c = 20.634（3）A, β= 92.209（2）°, V= 1861.2（4）A^3, Mr= 390.45, Z = 4, Dc = 1.393 g/cm^3,μ（MoKα） = 0.313 mm^-1, F（000） = 816, the final R = 0.0685 and wR = 0.1685. X-ray analysis reveals that two six-membered rings adopt chair and planar conformations, respectively.The title compound （C19H18O5S2） has been synthesized by the reaction of thio- phene-2-carboxaldehyde, isopropylidene malonate and 4-chloroaniline using [bmim]Br as solvent, and characterized by IR, ^1H NMR and X-ray single-crystal diffraction. The crystal belongs to monoclinic, space group P21/n with a = 9.4872（15）, b = 9.5148（13）, c = 20.634（3）A, β= 92.209（2）°, V= 1861.2（4）A^3, Mr= 390.45, Z = 4, Dc = 1.393 g/cm^3,μ（MoKα） = 0.313 mm^-1, F（000） = 816, the final R = 0.0685 and wR = 0.1685. X-ray analysis reveals that two six-membered rings adopt chair and planar conformations, respectively.

关 键 词：spiro[5.5]undecane crystal structure synthesis 

分 类 号：O626.12[理学—有机化学]