S-腺苷-L-蛋氨酸在弱酸树脂D113上的离子交换动力学研究  

STUDY ON ION-EXCHANGE DYNAMICS OF THE S-ADENOSYL-L-METHIONINE ON THE WEAK ACID D113 RESIN

作　　者：刘惠[1] 林建平[2] 岑沛霖[2] 

机构地区：[1]南京师范大学动力工程学院环境工程系,江苏南京210042 [2]浙江大学(玉泉)材化学院生物工程研究所,浙江杭州310027

出　　处：《离子交换与吸附》2008年第2期148-153,共6页Ion Exchange and Adsorption

摘　　要：考察了S-腺苷-L-蛋氨酸在弱酸树脂D113上的离子交换动力学。根据扩散控制模型,利用Fick定律关联计算得到有效内扩散系数D(数量级约为10-8cm2/s～10-9cm2/s)以及两相分配因子K,两者受浓度影响较大;进一步实验表明,较低的进样速度和较高的样品浓度利于提高分离得率和效率,是影响其分离的关键因素。The ion-exchange dynamics of S-adenosyl-L-methionine on weak acid cationic resin D113 were studied. According to diffusion controlled model, the effective diffusivity D, which was at the order of 10^-8m^2/s-10^-9cm^2/s, and partition factor K were correlated in different initial concentrations at 25℃ using Fick＇s law. Both them were sensitive to initial concentration in the investigated range. Further experiments on column separation indicated the low load rate and high concentration were beneficial to the product＇s recovery yield and separation efficiency.

关 键 词：S-腺苷-L-蛋氨酸 离子交换 弱酸树脂 动力学 Fick定律 分离 扩散系数 分配因子 

分 类 号：TQ028[化学工程]