吖啶红褪色光度法测定加替沙星的含量  

Fading spectrophotometric method for the determ ination of gatifloxacin with acridine red

作　　者：江虹[1] 李维[1] 

机构地区：[1]长江师范学院化学及环境科学系,重庆408003

出　　处：《化学研究与应用》2008年第4期449-451,共3页Chemical Research and Application

基　　金：重庆市教委科技基金项目(KJ051304)资助;教育部"春晖计划"项目(Z2005-1-55006)资助

摘　　要：Based on the color reactions of gatifloxacin with acridine red,a new fading spectrophotometric method for the determination of gatifloxacin has been established.In pH 3.0～4.2 acid condition,gatifloxacin reacts with acridine red to form peachblow complexes.At the maximum fading wavelength of 538nm,the apparent molar absorption coefficient(ε) was 1.32×104 L·mol-1·cm-1.The Beer’s law was obeyed in the concentration range of 0.2mg/L～15.0 mg/L.The method has been applied to determine gatifloxacin in the practical samples with satisfactory results.Based on the color reactions of gatifloxacin with acridine red, a new fading spectrophotometric method for the determination of gatifloxacin has been established. In pH 3.0 - 4. 2 acid condition, gatifloxacin reacts with acridine red to form peachblow complexes. At the maximum fading wavelength of538nm, the apparent molar absorption coefficient （ε） was 1.32 × 10^4 L·mol^-1·cm^-1. The Beer＇s law was obeyed in the concentration range of 0. 2mg/L ～ 15.0 mg/L. The method has been applied to determine gatifloxacin in the practical samples with satisfactory results.

关 键 词：加替沙星 吖啶红 分光光度法 

分 类 号：O657.32[理学—分析化学]