植物灭螺剂银杏酸对鱼的急性毒性研究  

Study on acute toxicity of ginkgolic acid against fish

作　　者：张联恒 吴向阳[2] 仰榴青[3] 张文莉[2] 葛琴娟 叶田田[2] 

机构地区：[1]江苏省镇江市疾病预防控制中心,镇江212003 [2]江苏大学化学化工学院 [3]江苏大学药学院

出　　处：《中国血吸虫病防治杂志》2008年第2期133-134,共2页Chinese Journal of Schistosomiasis Control

基　　金：国家自然科学基金(20672047);江苏省中医药局科研项目(H05006);江苏大学自然科学创新预研基金(04CX05)

摘　　要：目的观察银杏外种皮中的银杏酸对鱼的急性毒性。方法以银杏外种皮为原料,提取分离得银杏酸混合物,观察银杏酸药液对红鲤鱼苗和鲫鱼苗的急性毒性。结果银杏酸药液对红鲤鱼苗的LC50为1.805mg/L,LC90为2.191mg/L,对鲫鱼苗的LC50为1.930mg/L,LC90为2.217mg/L。结论银杏酸药液对2种鱼苗的毒性属中等。Objective To study the acute toxicity of ginkgolic acids from Ginkgo biloba sarcotestas against fish. Methods The ginkgolic acid mixture was obtained from Ginkgo biloba sarcotestas. The acute toxicities of the ginkgolic acid mixture against the fry of Cyprinus carpio var. and fry of Carassius auratus were detected. Results LC50 and LC90 of the ginkgolic acid mixture against the fry of Cyprinus carpio var. were 1. 805 mg/L and 2. 191 mg/L, respectively. LC50 and LC90 of the ginkgolic acid mixture against the fry of Carassius auratus were 1. 930 mg/L and 2. 217 mg/L, respectively. Conclusions The toxicity of ginkgolic acids against the fry of Cyprinus carpio var. and fry of Carassius auratus is medium.

关 键 词：银杏酸 银杏外种皮 鱼类 急性毒性 

分 类 号：R383.24[医药卫生—医学寄生虫学]