有机催化的不对称氧化反应  

Organocatalytic Asymmetric Oxidation

作　　者：宫斌[1] 孟庆伟[1] 高占先[1] 

机构地区：[1]大连理工大学精细化工国家重点实验室,大连116023

出　　处：《有机化学》2008年第4期588-597,共10页Chinese Journal of Organic Chemistry

摘　　要：有机催化剂在不对称氧化反应中显示出巨大应用潜力.综述了不同类型的有机催化剂催化的α,β-不饱和醛酮、烯烃的不对称环氧化反应及羰基化合物的不对称α-羟基化反应,并对催化特点及催化机理作了详细的描述.A great application potential of organocatalysts has been displayed in asymmetric oxidation. Asymmetric epoxidation of α,β-unsaturated aldehyde/ketone as well as olefin, and asymmetric α-hydroxylation of carbonyl compounds catalyzed by various types of organocatalysts are reviewed in this paper. The characteristics and mechanism of organocatalysis are also depicted in detail.

关 键 词：有机催化剂 不对称氧化 不对称环氧化 α-羟基化 

分 类 号：O621.251[理学—有机化学]