稀有放线菌产生的抗生素  

Antibiotics produced by rare actinomycetes

作　　者：李一青[1] 李艳琼[1] 李铭刚[1] 李勤[2] 赵江源[1] 崔晓龙[1] 彭谦[1] 文孟良[1] 

机构地区：[1]云南大学教育部微生物资源开放研究重点实验室云南省生物资源保护与利用重点实验室,昆明650091 [2]昆明市中医医院,昆明650011

出　　处：《中国抗生素杂志》2008年第4期193-197,共5页Chinese Journal of Antibiotics

基　　金：国家自然科学基金项目(20462008;30460004;30460022;20762012);云南省自然科学基金重点;面上项目(2004C0002Z;2006C0004M;2005PY01-1)资助

摘　　要：由于从链霉菌中发现新抗生素的几率越来越小,从稀有放线菌中寻找新抗生素成为研究的重点。稀有放线菌是新生物活性物质的重要产生菌,其产生的抗生素具有结构多样及活性独特的特点。本文概述近年来稀有放线菌中的小单孢菌属、诺卡菌属、马杜拉放线菌属、游动放线菌属、拟无枝菌酸菌属、小双孢菌属及糖多孢菌属等产生的抗生素种类及其活性。Searching for new antibiotics from rare actinomycetes has become the research focus because the rate of discovering novel antibiotics from streptomyces is significantly low. Rare actinomycetes are important producers for novel bioactive compounds ; and antibiotics produced by rare actinomycetes have characteristics of diversifying structures and unique bioactivity. In this paper, the structures and bioactivities of the antibiotics produced by rare actinomycetes, such as Micromonospora, Nocardia, Actinomadura, Actinoplanes,Amycolatopsis, Microbispora and Saccharopolyspora were summarized.

关 键 词：稀有放线菌 抗生素 活性物质 

分 类 号：Q939.99[生物学—微生物学]