院内泌尿系感染病原菌及耐药性研究  

Drug Resistance of Pathogens in Urinary Infection in Mountain Area Hospitals

作　　者：武怀书[1] 额尔敦[1] 卡索[1] 赵立强[1] 

机构地区：[1]解放军253医院感染控制科,内蒙古呼和浩特010051

出　　处：《中华医院感染学杂志》2008年第4期592-593,共2页Chinese Journal of Nosocomiology

摘　　要：目的调查院内尿路感染病原菌的现状及体外耐药性,为临床医生提供诊断和治疗依据。方法对2004年1月-2006年1月住院患者尿液培养中分离出的213株病原菌进行鉴定和体外耐药性试验。结果泌尿系感染菌株以大肠埃希菌(ECO)为主,占34.3%;其次为表皮葡萄球菌(SEP)、肠球菌属(ECN)、产气肠杆菌(EAE)、铜绿假单胞菌(PAE)、真菌;肠杆菌科对抗菌药物耐药率均较严重;革兰阳性球菌耐药率也相当严重。结论泌尿系感染最主要病原菌为大肠埃希菌,由于病原菌耐药率呈上升趋势,合理使用抗菌药物,重视病原菌的培养和药敏,是预防医院感染的重要措施。OBJECTIVE To summarize the present status and drug resistance of pathogens in hospital-acquired urinary system infection,and provide diagnostic and cure evidence for clinic physician.METHODS A total of 213 pathogen strains in urinary system infection from inpatients from Jan 2004 to Oct 2006 were identified and the drug resistance test was performed.RESULTS Escherichia coli rated the top one（34.3%）in urinary system infection,the following were Staphylococcus epidermidis,Enterococcus,Enterobacter aerogenes,Pseudomonas and fungi.The result of drug resistance test suggested that Enterobacteriaceae be resistant to several antibiotics,and Gram-positive cocci be also showed very serious drug resistance.CONCLUSIONS E.coli is the main infectious bacterium in urinary infection.As the rate of drug resistance rises,rational use of antibiotics according to urine culture results and drug sensitivity test is the very important way to prevent hospital infections.

关 键 词：泌尿系感染 病原菌 抗菌药物 耐药性 

分 类 号：R378[医药卫生—病原生物学]