脾动脉栓塞治疗特发性血小板减少性紫癜的临床观察  

Clinical Observation of Embolization Therapy of Splenic Artery in Idiopathic Thrombocytopenic Purpura

作　　者：邓元明[1] 张龙[1] 罗勇[2] 温云[2] 薛玉富[1] 牟方胜[2] 

机构地区：[1]重庆三峡中心医院介入科,重庆404000 [2]重庆三峡中心医院放射科,重庆404000

出　　处：《实用放射学杂志》2008年第4期540-542,共3页Journal of Practical Radiology

摘　　要：目的回顾性分析脾动脉栓塞治疗特发性血小板减少性紫癜的临床疗效。方法选择41例特发性血小板减少性紫癜内科用药无效情况下,采用Seldinger技术经右侧股动脉穿刺插管到脾动脉进行部分脾动脉栓塞,栓塞面积约80%左右。并于术后3d、1周、2周、1个月及对显效病例行3个月、半年、1年及2年复查血常规,并了解栓塞的疗效。结果术后1月血小板平均计数(210±50)×109/L,术后2年血小板平均计数(165±80)×109/L。术后显效27例占66%、良效8例占20%、进步3例占7%、无效3例占7%。结论部分脾动脉栓塞治疗特发性血小板减少性紫癜有一定疗效。Objective To analyze retrospectively the clinical effect of embolization therapy of splenic artery in idiopathic thrombocytopenic purpura. Methods 41 cases of idiopathic thrombocytopenic purpura failed by medicine therapy were treated with embolization of partly splenic artery using Seldinger technique. The embolic area of spleen was about 80%. The blood routine examinations were performed 3 days, 1 week,2 weeks and 1 month after operation in all cases,while for the effective cases of treatment,the blood routine examinations were performed 3 months, half a year, 1 year and 2 years later,and the therapeutic effect was evaluated. Results The platelets were increased up to （ 210 ±50 ） × 10^9/L after operation 1 months and （ 165 ± 80 ） ×10^9/L after 2 years. There were obvious effect in 27 cases（ 66% ） , good effect in 8 （ 20% ） ,effect in 3 （ 7% ） and no effect in 3 （ 7% ）. Conclusion The embolization therapy of partly splenic artery for idiopathic thrombocytopenic purpura is of certain therapeutic effect.

关 键 词：脾 特发性血小板减少性紫癜 栓塞 介入放射学 

分 类 号：R558.2[医药卫生—血液循环系统疾病] R815[医药卫生—内科学]